Not found SPECIAL TOPIC — Celebrating the 100th Anniversary of Physics Discipline of Northwest University

    This Special Topic was organized to celebrate the Centenary of Physics Discipline of Northwest University.

    Default Latest Most Read
    Please wait a minute...
    For selected: Toggle thumbnails
    Special breathing structures induced by bright solitons collision in a binary dipolar Bose-Einstein condensates
    Gen Zhang(张根), Li-Zheng Lv(吕李政), Peng Gao(高鹏), and Zhan-Ying Yang(杨战营)
    Chin. Phys. B, 2023, 32 (11): 110303.   DOI: 10.1088/1674-1056/acf283
    Abstract103)   HTML3)    PDF (970KB)(58)      
    We numerically investigate the breathing dynamics induced by collision between bright solitons in a binary dipolar Bose-Einstein condensates, whose dipole-dipole interaction and contact interaction are attractive. We identify three special breathing structures, such as snakelike special breathing structure, mixed breathing structure, and divide breathing structure. The characteristics of these breathing structures can be described by breathing frequency Ω, maximum breathing amplitude A and lifetime τ, which can be manipulated by atomic number Ni and interspecies scattering length a12. Meanwhile, the above breathing structures can realize the process of quasi-transition with a reasonable Ni and a12. Additionally, the collision of two special breathing structures also can bring more abundant breathing dynamics. Our results provide a reference for the study of soliton interactions and deepen the understanding of soliton properties in a binary dipolar Bose-Einstein condensates.
    Low-lying electronic states of osmium monoxide OsO
    Wen Yan(严汶) and Wenli Zou(邹文利)
    Chin. Phys. B, 2023, 32 (11): 113101.   DOI: 10.1088/1674-1056/acec46
    Abstract107)   HTML4)    PDF (5534KB)(76)      
    The ground state of osmium monoxide (OsO) has long been controversial. In this paper, the low-lying Λ-S and Ω electronic states of OsO have been comprehensively studied by the high-precision multi-reference calculations. The ground state of OsO is unexpectedly the closed-shell 1Σ+ state with a double bond instead of the previously reported 3Φ or 5Σ+ state; after including the spin-orbit coupling effects, the ground state becomes 3Π2. With the help of the theoretical spectroscopic constants and transition dipole moments, the emission spectra in the region of 405 nm-875 nm are assigned. Our results will facilitate the future studies of absorption and emission spectra of OsO.
    Vector fiber Bragg gratings accelerometer based on silicone compliant cylinder for low frequency vibration monitoring
    Wenyu Hu(胡文玉), Zhuo Chen(陈卓), Jiangshan You(尤江山), Ruohui Wang(王若晖), Rui Zhou(周锐), and Xueguang Qiao(乔学光)
    Chin. Phys. B, 2023, 32 (11): 114201.   DOI: 10.1088/1674-1056/acec43
    Abstract91)   HTML3)    PDF (1012KB)(72)      
    Vector accelerometer has attracted much attention for its great application potential in underground seismic signal measurement. We propose and demonstrate a novel vector accelerometer based on the three fiber Bragg gratings (FBGs) embedded in a silicone rubber compliant cylinder at 120° distributed uniformly. The accelerometer is capable of detecting the orientation of vibration with a range of 0°-360° and the acceleration through monitoring the central wavelength shifts of three FBGs simultaneously. The experimental results show that the natural frequency of the accelerometer is about 85 Hz, and the sensitivity is 84.21 pm/g in the flat range of m 20 Hz-60 Hz. Through experimental calibration, the designed accelerometer can accurately obtain vibration vector information, including vibration orientation and acceleration. In addition, the range of resonant frequency and sensitivity can be expanded by adjusting the hardness of the silicone rubber materials. Due to the characteristics of small size and orientation recognition, the accelerometer can be applied to low-frequency vibration acceleration vector measurement in narrow spaces.
    Topological resonators based on hexagonal-star valley photonic crystals
    Xin Wan(万鑫), Chenyang Peng(彭晨阳), Gang Li(李港), Junhao Yang(杨俊豪), and Xinyuan Qi(齐新元)
    Chin. Phys. B, 2023, 32 (11): 114208.   DOI: 10.1088/1674-1056/acf44b
    Abstract108)   HTML1)    PDF (4983KB)(98)      
    In valley photonic crystals, topological edge states can be gained by breaking the spatial inversion symmetry without breaking time-reversal symmetry or creating pseudo-spin structures, making highly unidirectional light transmission easy to achieve. This paper presents a novel physical model of a hexagonal-star valley photonic crystal. Simulations based on the finite element method (FEM) are performed to investigate the propagation of TM polarized mode and its application to ring resonators. The results show that such a topologically triangular ring resonator exhibits an optimum quality factor Q of about 1.25× 104, and Q has a maximum value for both frequency and the cavity length L. Our findings are expected to have significant implications for developing topological lasers and wavelength division multiplexers.
    High stability and low noise laser-diode end-pumped Nd: YAG ceramic passively Q-switched laser at 1123 nm based on a Ti3C2Tx-PVA saturable absorber
    Jia-Le Yan(闫佳乐), Ben Li(李奔), Guo-Zhen Wang(王国珍), Shun-Yu Yang(杨顺宇), Bao-Le Lu(陆宝乐), and Yang Bai(白杨)
    Chin. Phys. B, 2023, 32 (11): 114212.   DOI: 10.1088/1674-1056/acf495
    Abstract99)   HTML0)    PDF (4579KB)(85)      
    We report a high repetition frequency, high power stability and low laser noise laser-diode (LD) end-pumped Nd: YAG ceramic passively Q-switched laser at 1123 nm based on a Ti3C2Tx-polyvinyl alcohol (PVA) film as a saturable absorber (SA). A Brewster polarizer (BP) and a birefringent crystal (BC) are incorporated to enable frequency selection and filtering for the passively Q-switched 1123 nm pulsed laser to improve the power stability and reduce the noise. When the pump power is 5.1 W, an average output power of 457.9 mW is obtained, corresponding to a repetition frequency of 1.09 MHz, a pulse width of 56 ns, a spectral line width of 0.65 nm, a power instability of ± 0.92%, and a laser noise of 0.89%. The successful implementation of the “Ti3C2Tx-PVA film passively Q-switching” combined with “frequency selection and filtering of m BP + BC” technology path provides a valuable reference for developing pulsed laser with high repetition frequency, high stability and low noise.
    Topological states switching and group velocity control in two-dimensional non-reciprocal Hermitian photonic lattice
    Yu Lin(林宇), Yuandan Wang(王元旦), Junhao Yang(杨俊豪), Yixuan Fu(符艺萱), and Xinyuan Qi(齐新元)
    Chin. Phys. B, 2023, 32 (11): 114213.   DOI: 10.1088/1674-1056/ad0621
    Abstract89)   HTML2)    PDF (3188KB)(57)      
    We proposed a model with non reciprocal coupling coefficients, in which the imaginary parts γ indicate the phase delay or exceed term. The distributions of band structure and the group velocity are both characterized as a function of the coupling. we studied the system's topological states and group velocity control. The results show that the movement and breaking of Dirac points exist in the energy band of the system. By changing the coupling coefficients, the conversion between any topological states corresponds to different Chern number. Topological edge states exist in topological non-trivial systems that correspond to the two different Chern numbers. Besides, it is also found that both the coupling coefficient and the wave vector can cause the oscillation of the pulse group velocity. At the same time, the topological state can suppress the amplitude of the group velocity profiles. Our findings enrich the theory of light wave manipulation in high-dimensional photonic lattices and provide a novel view for realizing linear localization and group velocity regulation of light waves, which has potential application in high-speed optical communication and quantum information fields.
    Absorption spectra and enhanced Kerr nonlinearity in a four-level system
    Hao-Jie Huangfu(皇甫浩杰), Ying-Jie Du(杜英杰), and Ai-Hua Gao(高爱华)
    Chin. Phys. B, 2023, 32 (11): 114214.   DOI: 10.1088/1674-1056/ad0622
    Abstract108)   HTML0)    PDF (1818KB)(46)      
    In a coherent system, enhanced nonlinearity can be reached via far-detuned coupling fields in the presence of Autler-Townes splitting. We explore the absorption spectra and the Kerr nonlinearity of the coherent system via the interaction between a four-level atomic system and triple fields. We obtain the absorption spectra with double, triple and even quadruple peaks which depend on both the magnitude and the difference of the coupling fields. The Kerr nonlinearity always remains reversely correlated with the absorption spectra. We find that the large coupling detunings can lead to a significant growth of the Kerr nonlinearity and the degenerate four-wave mixing. Both the Kerr nonlinearity and the four-wave mixing can be managed by adjusting the detunings of the coupling fields.
    Bacterial turbulence in gradient confinement
    Ningzhe Yan(颜宁哲), Chenliang Xie(谢晨亮), Hao Luo(罗昊), Yanan Liu(刘亚楠), and Guangyin Jing(经光银)
    Chin. Phys. B, 2023, 32 (11): 114704.   DOI: 10.1088/1674-1056/acea6d
    Abstract87)   HTML0)    PDF (2490KB)(58)      
    We investigate a novel form of non-uniform living turbulence at an extremely low Reynolds number using a bacterial suspension confined within a sessile droplet. This turbulence differs from homogeneous active turbulences in two or three-dimensional geometries. The heterogeneity arises from a gradient of bacterial activity due to oxygen depletion along the droplet's radial direction. Motile bacteria inject energy at individual scales, resulting in local anisotropic energy fluctuations that collectively give rise to isotropic turbulence. We find that the total kinetic energy and enstrophy decrease as distance from the drop contact line increases, due to the weakening of bacterial activity caused by oxygen depletion. While the balance between kinetic energy and enstrophy establishes a characteristic vortex scale depending on the contact angle of the sessile drop. The energy spectrum exhibits diverse scaling behaviors at large wavenumber, ranging from k-1/5 to k-1, depending on the geometric confinement. Our findings demonstrate how spatial regulation of turbulence can be achieved by tuning the activity of driving units, offering insights into the dynamic behavior of living systems and the potential for controlling turbulence through gradient confinements.
    Straight and twisted Weyl nodal line phonons in Ho2CF2 material
    Xin-Yue Kang(康鑫越), Jin-Yang Li(李金洋), and Si Li(李思)
    Chin. Phys. B, 2023, 32 (11): 116301.   DOI: 10.1088/1674-1056/aceaea
    Abstract87)   HTML0)    PDF (1035KB)(56)      
    Based on first-principles calculations, symmetry analysis and model construction, we predict that Ho2CF2 hosts both straight and twisted Weyl nodal lines in its bulk phonon spectrum. We identify that the top two phonon bands entangle with each other, forming two straight Weyl nodal lines on the K-H and K'-H' paths at the Brillouin zone (BZ) boundary, and six twisted Weyl nodal lines within the BZ. All the Weyl nodal lines along the kz direction and across the entire BZ. The symmetry analysis indicates that these Weyl nodal lines are protected by the PT symmetry and crystal symmetry. The Berry phase and drumhead-like nontrivial surface states are calculated. We also construct a tight-binding model to describe these nodal lines. Our work provides an excellent material platform for exploring the fascinating physics associated with straight and twisted Weyl nodal line phonons.
    Interfacial photoconductivity effect of type-I and type-II Sb2Se3/Si heterojunctions for THz wave modulation
    Xue-Qin Cao(曹雪芹), Yuan-Yuan Huang(黄媛媛), Ya-Yan Xi(席亚妍), Zhen Lei(雷珍), Jing Wang(王静), Hao-Nan Liu(刘昊楠), Ming-Jian Shi(史明坚), Tao-Tao Han(韩涛涛), Meng-En Zhang(张蒙恩), and Xin-Long Xu(徐新龙)
    Chin. Phys. B, 2023, 32 (11): 116701.   DOI: 10.1088/1674-1056/acf301
    Abstract102)   HTML3)    PDF (696KB)(57)      
    An in-depth understanding of the photoconductivity and photocarrier density at the interface is of great significance for improving the performance of optoelectronic devices. However, extraction of the photoconductivity and photocarrier density at the heterojunction interface remains elusive. Herein, we have obtained the photoconductivity and photocarrier density of 173 nm Sb2Se3/Si (type-I heterojunction) and 90 nm Sb2Se3/Si (type-II heterojunction) utilizing terahertz (THz) time-domain spectroscopy (THz-TDS) and a theoretical Drude model. Since type-I heterojunctions accelerate carrier recombination and type-II heterojunctions accelerate carrier separation, the photoconductivity and photocarrier density of the type-II heterojunction (21.8× 104 S·m-1, 1.5× 1015 cm-3) are higher than those of the type-I heterojunction (11.8× 104 S·m-1, 0.8× 1015 cm-3). These results demonstrate that a type-II heterojunction is superior to a type-I heterojunction for THz wave modulation. This work highlights THz-TDS as an effective tool for studying photoconductivity and photocarrier density at the heterojunction interface. In turn, the intriguing interfacial photoconductivity effect provides a way to improve the THz wave modulation performance.
    Photo-responsive droplet manipulation slippery lubricant-infused porous surface with ultra-high durability
    Ze-Zhi Liu(刘泽志), Chen Zhang(张琛), Tong Wen(文通), Hui-Zhu Li(李荟竹), Wen-Ping Gao(高文萍), Xin-Kong Wang(王新孔), Wei Zhao(赵伟), Kai-Ge Wang(王凯歌), and Jin-Tao Bai(白晋涛)
    Chin. Phys. B, 2023, 32 (11): 116801.   DOI: 10.1088/1674-1056/ad0143
    Abstract98)   HTML2)    PDF (1282KB)(70)      
    Photo-responsive slippery lubricant-infused porous surface (SLIPS) for droplet manipulation is flexible, non-contact and non-destructive in droplet manipulation, which has promising applications in flexible robotics, microfluidics, biomedicine, and chemical analysis. However, the repeated manipulations for droplets of SLIPSs are quite limited in the works reported so far, the poor durability of droplet manipulation severely limits the practical application of the surfaces. In this paper, an Fe3O4-doped polydimethylsiloxane (PDMS)-based SLIPS is proposed and implemented to achieve ultra-high repeated droplet manipulation numbers under near-infrared ray (NIR) laser irradiation. Firstly, a micron columnar array structure with micro-pits on the top side, as well as, a wall structure out of the array is designed on SLIPS to reserve the lubricant. Secondly, the prototype of the SLIPS is fabricated by a 3-step ultraviolet (UV) lithography, and subsequently immersed in silicone oil for more than 96 h to obtain the ultra-high durability slippery lubricant-infused porous surface (UD-SLIPS). With a power of 25 mW-85 mW NIR laser, the repeated manipulation of microdroplets (≤ 5 μ L) in the scale of 1 cm can exceed more than 3000 times which is far beyond that in previous reports. Finally, the droplet manipulation performance of this photo-responsive UD-SLIPS and the influence of infusion time on durability are investigated. The mechanism of the PDMS swelling effect is found to be the key factor in improving the droplet manipulation durability of SLIPS. The findings of this work would be of great significance for the development of highly durable photo-responsive functional surfaces for droplet manipulation.
    Structural, electronic and magnetic properties of Fe-doped strontium ruthenates
    Nan Liu(刘楠), Xiao-Chao Wang(王晓超), and Liang Si(司良)
    Chin. Phys. B, 2023, 32 (11): 117101.   DOI: 10.1088/1674-1056/ad0112
    Abstract91)   HTML1)    PDF (2836KB)(63)      
    By employing a combined approach of density-functional theory (DFT) and dynamical mean-field theory (DMFT) calculations, we examine the structural, electronic, and magnetic characteristics of two distinct strontium ruthenates: Sr2RuO4, an unconventional superconductor, and the correlated metal SrRuO3, both at 50% Fe-doping level. In both Sr2Fe0.5Ru0.5O4 and SrFe0.5Ru0.5O3, the original ruthenium (Ru) and the dopant iron (Fe) atoms adopt 3-dimensional and 2-dimensional G-type structures, respectively. The hybridization between Fe-3d and Ru-4d is comparatively weaker than in other double perovskite systems. The interplay between strong correlations and reduced itinerancy results in significant spin splitting at Fe and Ru sites. Consequently, a charge transfer process, along with the super-exchange effect, leads to antiferromagnetically coupled Fe3+ and Ru5+ ions and establishes a semiconducting ferrimagnetic order. Subsequent DMFT calculations demonstrate the persistence of the ferrimagnetic order even at room temperature (300 K). These findings align with prior reports on SrFe0.5Ru0.5O3, thus reinforcing the notion that 3d-4d transition metal oxides hold considerable promise as candidates for high-performance spintronic devices, such as spin-valve sensors and spintronic giant magnetoresistance devices.
    Off-diagonal approach to the exact solution of quantum integrable systems
    Yi Qiao(乔艺), Junpeng Cao(曹俊鹏), Wen-Li Yang(杨文力), Kangjie Shi(石康杰), and Yupeng Wang(王玉鹏)
    Chin. Phys. B, 2023, 32 (11): 117504.   DOI: 10.1088/1674-1056/ad0774
    Abstract107)   HTML0)    PDF (665KB)(112)      
    We investigate the t-W scheme for the anti-ferromagnetic XXX spin chain under both periodic and open boundary conditions. We propose a new parametrization of the eigenvalues of the transfer matrix. Based on it, we obtain the exact solution of the system. By analyzing the distribution of zero roots at the ground state, we obtain the explicit expressions of the eigenfunctions of the transfer matrix and the associated $\mathbb{W}$ operator (see Eqs. (10) and (70)) in the thermodynamic limit. We find that the ratio of the quantum determinant with the eigenvalue of $\mathbb{W}$ operator for the ground state exhibits exponential decay behavior. Thus this fact ensures that the so-called inversion relation (the t-W relation without the W-term) can be used to study the ground state properties of quantum integrable systems with/without U(1)-symmetry in the thermodynamic limit.
    Temperature-dependent photoluminescence of lead-free cesium tin halide perovskite microplates
    Jiayu Tan(谭佳雨), Yixuan Zhou(周译玄), De Lu(卢德), Xukun Feng(冯旭坤), Yuqi Liu(刘玉琪), Mengen Zhang(张蒙恩), Fangzhengyi Lu(卢方正一), Yuanyuan Huang(黄媛媛), and Xinlong Xu(徐新龙)
    Chin. Phys. B, 2023, 32 (11): 117802.   DOI: 10.1088/1674-1056/ad028e
    Abstract100)   HTML0)    PDF (2283KB)(55)      
    Tin halide perovskites recently have attracted extensive research attention due to their similar electronic and band structures but non-toxicity compared with their lead analogues. In this work, we prepare high-quality CsSnX3 (X=Br, I) microplates with lateral sizes of around 1-4 μ m by chemical vapor deposition and investigate their low-temperature photoluminescence (PL) properties. A remarkable splitting of PL peaks of the CsSnBr3 microplate is observed at low temperatures. Besides the possible structural phase transition at below 70 K, the multi-peak fittings using Gauss functions and the power-dependent saturation phenomenon suggest that the PL could also be influenced by the conversion from the emission of bound excitons into free excitons. With the increase of temperature, the peak position shows a blueshift tendency for CsSnI3, which is governed by thermal expansion. However, the peak position of the CsSnBr3 microplate exhibits a transition from redshift to blueshift at ~ 160 K. The full width at half maximum of CsSnX3 broadens with increasing temperature, and the fitting results imply that longitudinal optical phonons dominate the electron-phonon coupling and the coupling strength is much more robust in CsSnBr3 than in CsSnI3. The PL intensity of CsSnX3 microplates is suppressed due to the enhanced non-radiative relaxation and exciton dissociation competing with radiative recombination. According to the Arrhenius law, the exciton binding energy of CsSnBr3 is ~ 38.4 meV, slightly smaller than that of CsSnI3.
    Fabrication and research of bi-functional CuNi2S4 nanosheets decorated TiO2/CuNi2S4 heterojunction photoanode for photoelectrochemical water splitting
    Wei Jin(金伟), Liyuan Zhang(张立媛), Wenjing Zhang(张文静), Qian Sun(孙倩), Dekai Zhang(张德恺), Hui Miao(苗慧), and Xiaoyun Hu(胡晓云)
    Chin. Phys. B, 2023, 32 (11): 118201.   DOI: 10.1088/1674-1056/acef06
    Abstract103)   HTML0)    PDF (3247KB)(65)      
    As a traditional n-type semiconductor, TiO2 has good UV absorption ability and stable physical and chemical properties. However, its wide band gap and low oxygen evolution reaction (OER) activity limit its application in the field of photoelectrochemical (PEC) water splitting. In this work, a type-II TiO2/CuNi2S4 heterojunction photoanode is successfully constructed, which expanded the light absorption range to visible and enhanced the OER activity. Firstly, TiO2 nanotubes (NTs) thin films are prepared on Ti substrates by two-step anodization, and then the bi-functional electrocatalytic material CuNi2S4 is grown on TiO2 NTs in the shape of nanosheets (NSs) in situ by solvothermal method. As a bi-functional electrocatalytic material, CuNi2S4 has good visible light absorption property as well as OER catalytic activity. Compared with TiO2, the IPCE value of TiO2/CuNi2S4 is 2.59% at 635 nm, and that of TiO2 is a mere 0.002%. The separation efficiency and injection efficiency increase from 2.49% and 31.52% to 3.61% and 87.77%, respectively. At 1.23 V vs. RHE, the maximum photocurrent density is 0.26 mA/cm2, which is 2.6 times than that of TiO2 (0.11 mA/cm2), and can be maintained at 0.25 mA/cm2 for at least 2 h under light illumination. Moreover, a hydrogen production rate of 4.21 μ mol· cm-2·h-1 is achieved within 2 h. This work provides a new idea for the application of TiO2 in the field of PEC water splitting and the construction of efficient and stable photoelectronic devices.
    A fast-response self-powered UV-Vis-NIR broadband photodetector based on a AgIn5Se8/t-Se heterojunction
    Kang Li(李康), Lei Xu(许磊), Qidong Lu(陆启东), and Peng Hu(胡鹏)
    Chin. Phys. B, 2023, 32 (11): 118503.   DOI: 10.1088/1674-1056/acec44
    Abstract101)   HTML0)    PDF (4115KB)(28)      
    A type II p-n heterojunction could improve the photodetection performance of a photodetector due to the excellent ability of carrier separation. N-type AgIn5Se8 (AIS) exhibits a large optical absorption coefficient, high optical conductivity and a suitable bandgap, and shows potential application in broadband photodetection. Even though our previous study on AgIn5Se8/FePSe3 obtained a good response speed, it still gave low responsivity due to the poor quality of the p-type FePSe3 thin film. Se, with a direct bandgap (around 1.7 eV), p-type conductivity, high electron mobility and high carrier density, is likely to form a low-dimensional structure, which leads to an increase in the effective contact area of the heterojunction and further improves the photodetector performance. In this work, continuous and dense t-Se thin film was prepared by electrochemical deposition. The self-powered AgIn5Se8/t-Se heterojunction photodetector exhibited a broadband detection range from 365 nm to 1200 nm. The responsivity and detectivity of the heterojunction photodetector were 32 μ A/W and 1.8× 109 Jones, respectively, which are around 9 and 4 times higher than those of the AgIn5Se8/FePSe3 heterojunction photodetector. The main reason for this is the good quality of the t-Se thin film and the formation of the low-dimensional t-Se nanoribbons, which optimized the transport pathway of carriers. The results indicate that the AgIn5Se8/t-Se heterojunction is an excellent candidate for broadband and self-powered photoelectronic devices.
    Reconstructing in vivo spatially offset Raman spectroscopy of human skin tissue using a GPU-accelerated Monte Carlo platform
    Yun-He Zhang(张云鹤), Huan-Zheng Zhu(朱桓正), Yong-Jiang Dong(董泳江), Jia Zeng(曾佳), Xin-Peng Han(韩新鹏), Ivan A. Bratchenko, Fu-Rong Zhang(张富荣), Si-Yuan Xu(许思源), and Shuang Wang(王爽)
    Chin. Phys. B, 2023, 32 (11): 118702.   DOI: 10.1088/1674-1056/acef05
    Abstract87)   HTML0)    PDF (3104KB)(48)      
    As one type of spatially offset Raman spectroscopy (SORS), inverse SORS is particularly suited to in vivo biomedical measurements due to its ring-shaped illumination scheme. To explain inhomogeneous Raman scattering during in vivo inverse SORS measurements, the light-tissue interactions when excitation and regenerated Raman photons propagate in skin tissue were studied using Monte Carlo simulation. An eight-layered skin model was first built based on the latest transmission parameters. Then, an open-source platform, Monte Carlo eXtreme (MCX), was adapted to study the distribution of 785 nm excitation photons inside the model with an inverse spatially shifted annular beam. The excitation photons were converted to emission photons by an inverse distribution method based on excitation flux with spatial offsets Δs of 1 mm, 2 mm, 3 mm and 5 mm. The intrinsic Raman spectra from separated skin layers were measured by continuous linear scanning to improve the simulation accuracy. The obtained results explain why the spectral detection depth gradually increases with increasing spatial offset, and address how the intrinsic Raman spectrum from deep skin layers is distorted by the reabsorption and scattering of the superficial tissue constituents. Meanwhile, it is demonstrated that the spectral contribution from subcutaneous fat will be improved when the offset increases to 5 mm, and the highest detection efficiency for dermal layer spectral detection could be achieved when Δs = 2 mm. Reasonably good matching between the calculated spectrum and the measured in vivo inverse SORS was achieved, thus demonstrating great utility of our modeling method and an approach to help understand the clinical measurements.
    Assessing pathological features of breast cancer via the multimodal information of multiphoton and Raman imaging
    Bing-Ran Gao(高冰然), Xi-Wen Chen(陈希文), Bao-Ping Zhang(张宝萍), Ivan A. Bratchenko, Jian-Xin Chen(陈建新), Shuang Wang(王爽), and Si-Yuan Xu(许思源)
    Chin. Phys. B, 2023, 32 (11): 118703.   DOI: 10.1088/1674-1056/acea67
    Abstract92)   HTML2)    PDF (3438KB)(32)      
    For unveiling the pathological evolution of breast cancer, nonlinear multiphoton microscopic (MPM) and confocal Raman microspectral imaging (CRMI) techniques were both utilized to address the structural and constitutional characteristics of healthy (H), ductal carcinoma in situ (DCIS), and invasive ductal carcinoma (IDC) tissues. MPM-based techniques, including two-photon excited fluorescence (TPEF) and second harmonic generation (SHG), visualized label-free and the fine structure of breast tissue. Meanwhile, CRMI not only presented the chemical images of investigated samples with the K-mean cluster analysis method (KCA), but also pictured the distribution of components in the scanned area through univariate imaging. MPM images illustrated that the cancer cells first arranged around the basement membrane of the duct, then proliferated to fill the lumens of the duct, and finally broke through the basement membrane to infiltrate into the stroma. Although the Raman imaging failed to visualize the cell structure with high resolution, it explained spectroscopically the gradual increase of nucleic acid and protein components inside the ducts as cancer cells proliferated, and displayed the distribution pattern of each biological component during the evolution of breast cancer. Thus, the combination of MPM and CRMI provided new insights into the on-site pathological diagnosis of malignant breast cancer, also ensured technical support for the development of multimodal optical imaging techniques for precise histopathological analysis.
    Effect of mono-/divalent metal ions on the conductivity characteristics of DNA solutions transferring through a microfluidic channel
    Jie Zhu(朱洁), Jing Xue(薛菁), Wei Zhao(赵伟), Chen Zhang(张琛), Xiaoqiang Feng(冯晓强), and Kaige Wang(王凯歌)
    Chin. Phys. B, 2023, 32 (11): 118704.   DOI: 10.1088/1674-1056/acfaf6
    Abstract114)   HTML0)    PDF (1892KB)(59)      
    Interactions between deoxyribonucleic acid (DNA) and metal ions are vital for maintaining life functions, however, there are still unsolved questions about its mechanisms. It is of great practical significance to study these issues for medical chip design, drug development, health care, etc. In this investigation, the conductivity properties of λ -DNA solutions with mono-/divalent metal ions (Na+, K+, Mg2+, and Ca2+) are experimentally studied as they are electrically driven through a 5 μ m microfluidic channel. Experimental data indicate that the conductivities of λ -DNA solutions with metal ions (M+/M2+) basically tend to reduce firstly and then increase as the voltage increases, of which the turning points varied with the metal ions. When the voltage surpasses turning points, the conductivity of λ -DNA-M+ solutions increases with the concentration of metal ions, while that of λ -DNA-M2+ solutions decrease. Moreover, the conductivity of λ -DNA-M2+ solutions is always smaller than that of λ -DNA-M+ solutions, and with high-concentration M2+, it is even smaller than that of the λ -DNA solution. The main reasons for the above findings could be attributed to the polarization of electrodes and different mechanisms of interactions between metal ions and λ -DNA molecules. This investigation is helpful for the precise manipulation of single DNA molecules in micro-/nanofluidic space and the design of new biomedical micro-/nanofluidic sensors.
    Directional-to-random transition of cell cluster migration
    Yang Zeng(曾阳), Bingchen Che(车丙晨), Dan Sun(孙聃), Ce Zhang(张策), and Guangyin Jing(经光银)
    Chin. Phys. B, 2023, 32 (11): 118705.   DOI: 10.1088/1674-1056/acf704
    Abstract103)   HTML0)    PDF (1308KB)(53)      
    Efficient cell migration is crucial for the functioning of biological processes, e.g., morphogenesis, wound healing, and cancer metastasis. In this study, we monitor the migratory behavior of the 3D fibroblast clusters using live cell microscopy, and find that crowded environment affects cell migration, i.e., crowding leads to directional migration at the cluster's periphery. The number of cell layers being stacked during seeding determines the directional-to-random transition. Intriguingly, the migratory behavior of cell clusters resembles the dispersion dynamics of clouds of passive particles, indicating that the biological process is driven by physical effects (e.g., entropy) rather than cell communication. Our findings highlight the role of intrinsic physical characteristics, such as crowding, in regulating biological behavior, and suggest new therapeutic approaches targeting at cancer metastasis.