Measurement of T wave in magnetocardiography using tunnel magnetoresistance sensor
Zhihong Lu(陆知宏)1,2,3, Shuai Ji(纪帅)1,2,3, and Jianzhong Yang(杨建中)1,2,3,†
1 Department of Precision Instrument, Tsinghua University, Beijing 100084, China; 2 Beijing Innovation Center for Future Chips, Beijing 100084, China; 3 State Key Laboratory of Precision Measurement Technology and Instruments, Tsinghua University, Beijing 100084, China
Abstract Several critical clinical applications of magnetocardiography (MCG) involve its T wave. The T wave's accuracy directly affects the diagnostic accuracy of MCG for ischemic heart disease and arrhythmogenic. Tunnel magnetoresistance (TMR) attracts attention as a new MCG measurement technique. However, the T waves measured by TMR are often drowned in noise. The accuracy of T waves needs to be discussed to determine the clinical value of MCG measured by TMR. This study uses an improved empirical mode decomposition (EMD) algorithm and averaging to eliminate the noise in the MCG measured by TMR. The MCG signals measured by TMR are compared with MCG measured by the optically pumped magnetometer (OPM) to judge its accuracy. Using the MCG measured by OPM as a reference, the relative errors in time and amplitude of the T wave measured by TMR are 3.4% and 1.8%, respectively. This is the first demonstration that TMR can accurately measure the time and amplitude of MCG T waves. The ability to provide reliable T wave data illustrates the significant clinical application value of TMR in MCG measurement.
Fund: Project supported by the Suzhou Tsinghua innovation leading action project (Grant No. 2016SZ0217) and the National Key Research and Development Program of China (Grant No. 2016YFB0500902).
Corresponding Authors:
Jianzhong Yang
E-mail: yang-jz@tsinghua.edu.cn
Cite this article:
Zhihong Lu(陆知宏), Shuai Ji(纪帅), and Jianzhong Yang(杨建中) Measurement of T wave in magnetocardiography using tunnel magnetoresistance sensor 2023 Chin. Phys. B 32 020703
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