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Chin. Phys. B, 2014, Vol. 23(4): 048702    DOI: 10.1088/1674-1056/23/4/048702
INTERDISCIPLINARY PHYSICS AND RELATED AREAS OF SCIENCE AND TECHNOLOGY Prev   Next  

Cardiac electrical activity imaging of patients with CRBBB or CLBBB in magnetocardiography

Zhu Jun-Jie (朱俊杰)a, Jiang Shi-Qin (蒋式勤)a, Wang Wei-Yuan (王伟远)a, Zhao Chen (赵晨)a, Wu Yan-Hua (吴燕华)a, Luo Ming (罗明)b, Quan Wei-Wei (权薇薇)c
a Department of Control Science and Engineering, School of Electronics and Information Engineering, Tongji University, Shanghai 201804, China;
b Department of Cardiology of Tongji Hospital Affiliated to Tongji University Medical School, Shanghai 200065, China;
c Department of Cardiology of Ruijin Hospital Affiliated to Jiaotong University Medical School, Shanghai 200025, China
Abstract  A new method for the imaging of cardiac electrical activity in patients with complete right bundle branch block (CRBBB) or complete left bundle branch block (CLBBB) is investigated using magnetocardiographic recordings of the surface of the body. This is based on the assumption that an equivalent single-current dipole moves along the unblocked bundle branch, whose position in the measurement plane is expressed in terms of the maximum and minimum, as well as the maximum gradient value of the measured magnetic field. The trajectory of the moving dipole on the measurement plane is indicative of the excitation conduction of the CRBBB or CLBBB subject during ventricular depolarization and repolarization, which is deduced by comparing each change between the dipole moment and the maximum current density in a corresponding pseudo-current density map. In summary, this method can distinguish CRBBB from CLBBB subjects by means of the dipole depth and two dipole moment components. The possibility of visualizing the excitation conduction in a CRBBB or CLBBB subject during ventricular depolarization and repolarization is then discussed.
Keywords:  biomagnetism      inverse problem      magnetocardiography (MCG)      current source reconstruction (CSR)      CRBBB or CLBBB  
Received:  07 September 2013      Revised:  05 November 2013      Accepted manuscript online: 
PACS:  87.85.-d (Biomedical engineering)  
  87.85.Pq (Biomedical imaging)  
  87.85.Tu (Modeling biomedical systems)  
  87.85.Ng (Biological signal processing)  
Fund: Project supported in part by the National Natural Science Foundation of China (Grant No. 60771030), the National High-Technology Research and Development Program of China (Grant No. 2008AA02Z308), the Shanghai Science and Technology Development Foundation (Grant No. 08JC1421800), the Shanghai Leading Academic DisciplineProject (Grant No. B004), the OpenProject of State Key Laboratory of Function Materials for Information (Shanghai Institute of Microsystem and Information Technology, Chinese Academy of Sciences), and the Key Laboratory of Medical Imaging Computing and Computer Assisted Intervention of Shanghai (Grant No. 13DZ2272200-2).
Corresponding Authors:  Jiang Shi-Qin     E-mail:  sqjiang@tongji.edu.cn
About author:  87.85.-d; 87.85.Pq; 87.85.Tu; 87.85.Ng

Cite this article: 

Zhu Jun-Jie (朱俊杰), Jiang Shi-Qin (蒋式勤), Wang Wei-Yuan (王伟远), Zhao Chen (赵晨), Wu Yan-Hua (吴燕华), Luo Ming (罗明), Quan Wei-Wei (权薇薇) Cardiac electrical activity imaging of patients with CRBBB or CLBBB in magnetocardiography 2014 Chin. Phys. B 23 048702

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