Study on conversion of microstates in breast cell ensemble at the gene level based on the eigen-microstate method

doi:10.1088/1674-1056/acb9f8

Abstract Breast cancer is a malignant disease that seriously threatens women's health. Studying the mechanism of cancer occurrence and development is an urgent problem to be solved. In this paper, the eigen-microstate method was used to study conversion of normal breast cells into breast cancer cells and the reason. The main conclusions are as follows: the microstates of normal breast cell and breast cancer cell are different. There is a state conversion when a normal breast cell transforms into a breast cancer cell. The main reason for this state conversion is the combined effect of tumor suppressor genes and oncogenes. By analyzing the function of key genes, it was found that these genes do play an important role in the development of breast cancer. The findings contribute to understanding the mechanism by which breast cancer occurs and progresses, and key genes can serve as potential biomarkers or target genes for breast cancer treatment.

Keywords: eigen-microstate conversion breast cancer key genes

Received: 26 October 2022
Revised: 19 December 2022
Accepted manuscript online: 08 February 2023

PACS:	05.70.Fh	(Phase transitions: general studies)
	87.10.-e	(General theory and mathematical aspects)
	87.19.xj	(Cancer)
	89.75.-k	(Complex systems)

Fund: We thank our colleagues who have contributed to the work described herein, and apologize to those whose work we could not cite due to the space issue. Project supported by the National Natural Science Foundation of China (Grant No. 11735006).

Corresponding Authors: Yong Zhan
E-mail: zhany@hebut.edu.cn

Cite this article:

Su-Hua Zhang(张素花), Xue-Zhi Niu(牛雪芝), Xu-Zhao Wang(王徐朝), Chang Qu(屈畅), Hai-Long An(安海龙), Tong-Jun Zhao(赵同军), and Yong Zhan(展永) Study on conversion of microstates in breast cell ensemble at the gene level based on the eigen-microstate method 2023 Chin. Phys. B 32 050504

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