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Chin. Phys. B, 2012, Vol. 21(3): 038701    DOI: 10.1088/1674-1056/21/3/038701
INTERDISCIPLINARY PHYSICS AND RELATED AREAS OF SCIENCE AND TECHNOLOGY Prev   Next  

Two-dimensional model of elastically coupled molecular motors

Zhang Hong-Wei(张红卫)a)b), Wen Shu-Tang(文书堂)a)c)†, Chen Gai-Rong(陈改荣)c), Li Yu-Xiao(李玉晓)a), Cao Zhong-Xing(曹中兴)c), and Li Wei(李伟)c)
a. School of Physics and Engineering, Zhengzhou University, Zhengzhou 450052, China;
b. Department of Physics, Zhengzhou Normal University, Zhengzhou 450044, China;
c. School of Chemistry and Chemical Engineering, Xinxiang University, Xinxiang 453003, China
Abstract  A flashing ratchet model of a two-headed molecular motor in a two-dimensional potential is proposed to simulate the hand-over-hand motion of kinesins. Extensive Langevin simulations of the model are performed. We discuss the dependences of motion and efficiency on the model parameters, including the external force and the temperature. A good qualitative agreement with the expected behavior is observed.
Keywords:  Brownian motors      ratchet      current      efficiency  
Received:  04 June 2011      Revised:  15 September 2011      Accepted manuscript online: 
PACS:  87.15.B- (Structure of biomolecules)  
  87.15.H- (Dynamics of biomolecules)  
  87.15.R- (Reactions and kinetics)  
  87.15.La (Mechanical properties)  
Fund: Project supported by the Educational Commission of Henan Province, China (Grant No. 2006140015) and the Science and Technology Planning Project of Henan Province, China (Grant No. 092300410142).
Corresponding Authors:  Wen Shu-Tang,wensttnn@163.com     E-mail:  wensttnn@163.com

Cite this article: 

Zhang Hong-Wei(张红卫), Wen Shu-Tang(文书堂), Chen Gai-Rong(陈改荣), Li Yu-Xiao(李玉晓), Cao Zhong-Xing(曹中兴), and Li Wei(李伟) Two-dimensional model of elastically coupled molecular motors 2012 Chin. Phys. B 21 038701

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