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Low-energy termination of spiral turbulence in heterogeneous myocardium using circularly polarized electric fields |
| Yu-Jie Lv(吕玉杰)1, Xia Feng(冯霞)1,†, Wan-Jie Mei(梅万杰)1, Kai-Wen Sun(孙凯文)1, Chun Zhang(张春)1, and Xiang Gao(高翔)2,‡ |
1 Faculty of Science, Xi'an Shiyou University, Xi'an 710065, China;
2 School of Physics and Information Technology, Shaanxi Normal University, Xi'an 710062, China |
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Abstract Circularly polarized electric fields (CPEF) represent a highly promising low-energy defibrillation approach, demonstrating exceptional efficacy in terminating life-threatening arrhythmias such as ventricular fibrillation while effectively mitigating the myocardial injury risks associated with conventional high-voltage defibrillation. This study provides an in-depth revelation of the mechanism by which CPEF induces excitation waves around naturally occurring heterogeneous defects within heart tissue, thereby suppressing spiral turbulence. Through numerical simulations based on the LR1 model and phase field method, we confirm that CPEF, due to its dynamic rotational properties, induces virtual electrode effects around various defects. In conditions of low strength, CPEF adaptively excites these defects, thereby achieving synchronized myocardial activation for defibrillation. In comparison with uniform electric fields (UEF), CPEF is more effective in suppressing spiral turbulence by inducing periodic excitation waves around defects with irregular geometries. These findings elucidate the biophysical principles underlying CPEF’s low-energy defibrillation capability, offering robust theoretical support for developing non-invasive antiarrhythmic therapies.
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Received: 14 September 2025
Revised: 08 November 2025
Accepted manuscript online: 27 November 2025
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PACS:
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82.40.Ck
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(Pattern formation in reactions with diffusion, flow and heat transfer)
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87.18.Hf
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(Spatiotemporal pattern formation in cellular populations)
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87.19.lp
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(Pattern formation: activity and anatomic)
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| Fund: Project supported by the National Natural Science Foundation of China (Grant No. 11647055), the Natural Science Basic Research Program of Shaanxi Province (Grant Nos. 2024JC-YBMS-073, 2024JC-YBMS-074, and 2023-JCQN-0013), the Scientific Research Program Funded by Shaanxi Provincial Education Department (Grant No. 23JK0604), and the National College Students Innovation and Entrepreneurship Training Program of Xi’an Shiyou University (Grant No. 202310705020). |
Corresponding Authors:
Xia Feng, Xiang Gao
E-mail: fengxia0709@126.com;gaoxiang.gnaixoag@gmail.com
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Cite this article:
Yu-Jie Lv(吕玉杰), Xia Feng(冯霞), Wan-Jie Mei(梅万杰), Kai-Wen Sun(孙凯文), Chun Zhang(张春), and Xiang Gao(高翔) Low-energy termination of spiral turbulence in heterogeneous myocardium using circularly polarized electric fields 2026 Chin. Phys. B 35 038201
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