A non-Markov ratchet model of molecular motors: processive movement of single-headed kinesin KIF1A
Xie Ping (谢平), Dou Shuo-Xing (窦硕星), Wang Peng-Ye (王鹏业)
Laboratory of Soft Matter Physics, Beijing National Laboratory for Condensed Matter Physics, Institute of Physics, Chinese Academy of Sciences,Beijing 100080, China
Abstract A fluctuating ratchet model of non-Markov process is presented to describe the processive movement of molecular motors of single-headed kinesin KIF1A,where the fluctuation perturbation to the local potential is introduced and the detailed ATPase pathway of the motor is included. The theoretical results show good quantitative agreement with the previous experimental ones.
Received: 20 September 2005
Revised: 22 November 2005
Accepted manuscript online:
Fund: Project supported by the National Natural Science Foundation of China (Nos. 60025516 and 10334100).
Cite this article:
Xie Ping (谢平), Dou Shuo-Xing (窦硕星), Wang Peng-Ye (王鹏业) A non-Markov ratchet model of molecular motors: processive movement of single-headed kinesin KIF1A 2006 Chinese Physics 15 536
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