Spatiotemporal multiple coherence resonances and calcium waves in a coupled hepatocyte system
Wang Bao-Hua(王宝华)a)b), Lu Qi-Shao(陆启韶)a)†, Lü Shu-Juan(吕淑娟)a), and Lang Xiu-Feng(郎秀锋)a)
a School of Science, Beijing University of Aeronautics-Astronautics, Beijing 100191, China; b College of Mathematics Science, Heilongjiang University, Harbin 150080, China
Abstract Spatiotemporal multiple coherence resonances for calcium activities induced by weak Gaussian white noise in coupled hepatocytes are studied. It is shown that bi-resonances in hepatocytes are induced by the interplay and competition between noise and coupling of cells, in other words, the cell in network can be excited either by noise or by its neighbour via gap junction which can transfer calcium ions between cells. Furthermore, the intercellular annular calcium waves induced by noise are observed, in which the wave length decreases with noise intensity augmenting but increases monotonically with coupling strength increasing. And for a fixed noise level, there is an optimal coupling strength that makes the coherence resonance reach maximum.
Received: 19 July 2008
Revised: 29 August 2008
Accepted manuscript online:
PACS:
87.18.Hf
(Spatiotemporal pattern formation in cellular populations)
Fund: Project supported by the National
Natural Science Foundation of China (Grant Nos 10432010 and
10872014).
Cite this article:
Wang Bao-Hua(王宝华), Lu Qi-Shao(陆启韶), Lü Shu-Juan(吕淑娟), and Lang Xiu-Feng(郎秀锋) Spatiotemporal multiple coherence resonances and calcium waves in a coupled hepatocyte system 2009 Chin. Phys. B 18 872
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