Proteins：From sequence to structure

doi:10.1088/1674-1056/23/7/078705

Abstract Protein sequences as special heterogeneous sequences are rare in the amino acid sequence space. The specific sequential order of amino acids of a protein is essential to its 3D structure. On the whole, the correlation between sequence and structure of a protein is not so strong. How well would a protein sequence contain its structural information? How does a sequence determine its native structure? Keeping the globular proteins in mind, we discuss several problems from sequence to structure.

Keywords: proteins protein sequence protein structures protein folding

Received: 02 March 2014
Revised: 13 June 2014
Accepted manuscript online:

PACS:	87.14.E
	87.15.B
	87.15.Cc	(Folding: thermodynamics, statistical mechanics, models, and pathways)

Fund: Project supported by the National Natural Science Foundation of China (Grant Nos. 11175224 and 11121403).

Corresponding Authors: Zheng Wei-Mou
E-mail: zheng@itp.ac.cn

About author: 87.14.E; 87.15.B; 87.15.Cc

Cite this article:

Zheng Wei-Mou (郑伟谋) Proteins：From sequence to structure 2014 Chin. Phys. B 23 078705

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