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Simulation study of a magnetocardiogram based on a virtual heart model: effect of a cardiac equivalent source and a volume conductor |
Shou Guo-Fa(寿国法)a), Xia Ling(夏灵) a)†, Ma Ping(马平)b), Tang Fa-Kuan(唐发宽)c)‡, and Dai Ling(戴灵)a) |
a Department of Biomedical Engineering, Key Laboratory for Biomedical Engineering of the Ministry of Education, Zhejiang University, Hangzhou 310027, China; b Department of Physics, State Key Laboratory for Artificial Microstructure and Mesoscopic Physics, Peking University, Beijing 100871, China; c Department of Cardiology, the 309th Hospital of the People's Liberation Army, Beijing 100091, China |
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Abstract In this paper, we present a magnetocardiogram (MCG) simulation study using the boundary element method (BEM) and based on the virtual heart model and the realistic human volume conductor model. The different contributions of cardiac equivalent source models and volume conductor models to the MCG are deeply and comprehensively investigated. The single dipole source model, the multiple dipoles source model and the equivalent double layer (EDL) source model are analysed and compared with the cardiac equivalent source models. Meanwhile, the effect of the volume conductor model on the MCG combined with these cardiac equivalent sources is investigated. The simulation results demonstrate that the cardiac electrophysiological information will be partly missed when only the single dipole source is taken, while the EDL source is a good option for MCG simulation and the effect of the volume conductor is smallest for the EDL source. Therefore, the EDL source is suitable for the study of MCG forward and inverse problems, and more attention should be paid to it in future MCG studies.
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Received: 05 August 2010
Revised: 08 September 2010
Accepted manuscript online:
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PACS:
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07.05.Tp
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(Computer modeling and simulation)
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Fund: Project supported by the State Key Development Program for Basic Research of China (Grant Nos. 2007CB512100 and 2006CB601007), the National Natural Science Foundation of China (Grant No. 10674006), the National High Technology Research and Development Program of China (Grant No. 2007AA03Z238), China Postdoctoral Science Foundation (Grant No. 20090461376), and the Fundamental Research Funds for the Central Universities (Grant No. KYJD09001). |
Cite this article:
Shou Guo-Fa(寿国法), Xia Ling(夏灵), Ma Ping(马平), Tang Fa-Kuan(唐发宽), and Dai Ling(戴灵) Simulation study of a magnetocardiogram based on a virtual heart model: effect of a cardiac equivalent source and a volume conductor 2011 Chin. Phys. B 20 030702
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