Application of microdosimetry on biological physics for ionizing radiation

doi:10.1088/1674-1056/27/2/028701

Abstract

Stochastic characterization of radiation interaction is of importance to cell damage. Microdosimetry is to investigate the random structures of particle tracks in order to understand the dose-effect in cellular scales. In the review, we introduced the basic concepts of microdosimetry as well as the experimental methods (TEPC) and Monte Carlo simulations. Three basic biophysical models are interpreted and compared, including the target model, linear-quadratic model, and microdosimetric-kinetic model. The bottlenecks in the current microdosimetry research are also discussed, which need the interdisciplinary contributions from biology, physics, mathematics, computer science and electric engineering.

Keywords: microdosimetry biophysics radiation protection

Received: 08 October 2017
Revised: 30 November 2017
Accepted manuscript online:

PACS:	87.10.Mn	(Stochastic modeling)
	87.10.Rt	(Monte Carlo simulations)
	87.57.uq	(Dosimetry)

Fund:

Project supported by the National Natural Science Foundation of China (Grant Nos. 11304212 and 11575124), the Natural Science Foundation of Jiangsu Province, China (Grant Nos. BK20130279), the Priority Academic Program Development of Jiangsu Higher Education Institutions (PAPD), and the International Thermonuclear Experimental Reactor (ITER) Special Program of China (Grant No. 2014GB112006).

Corresponding Authors: Liang Sun
E-mail: slhmz@126.com

About author: 87.10.Mn; 87.10.Rt; 87.57.uq

Cite this article:

Dandan Chen(陈丹丹), Liang Sun(孙亮) Application of microdosimetry on biological physics for ionizing radiation 2018 Chin. Phys. B 27 028701

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