Influence of matrigel on the shape and dynamics of cancer cells

doi:10.1088/1674-1056/ab4275

中国物理B ›› 2019, Vol. 28 ›› Issue (10): 108704-108704.doi: 10.1088/1674-1056/ab4275

• SPECIAL TOPIC—Recent advances in thermoelectric materials and devices • 上一篇下一篇

Influence of matrigel on the shape and dynamics of cancer cells

Teng Ye(叶腾), Feng Qiu(邱峰)

First Clinical Medical College, Nanchang University, Nanchang, China, Department of Oncology, First Affiliated Hospital of Nanchang University, Nanchang, China

收稿日期:2019-08-28 修回日期:2019-09-06 出版日期:2019-10-05 发布日期:2019-10-05
通讯作者: Feng Qiu E-mail:lukeqiubmu@163.com

Influence of matrigel on the shape and dynamics of cancer cells

Teng Ye(叶腾)¹, Feng Qiu(邱峰)^1,2

First Clinical Medical College, Nanchang University, Nanchang, China, Department of Oncology, First Affiliated Hospital of Nanchang University, Nanchang, China

Received:2019-08-28 Revised:2019-09-06 Online:2019-10-05 Published:2019-10-05
Contact: Feng Qiu E-mail:lukeqiubmu@163.com

摘要/Abstract

摘要：

The interaction between extracellular matrices and cancer cells plays an important role in regulating cancer cell behaviors. In this article, we use matrigel to mimic extracellular matrices and investigate experimentally how matrigel influences the shape and dynamics of breast cancer cells (MDA-MB-231-GFP cells). We find that matrigel facilitates cancer cells' migration and shape deformation. The influences of the matrigel concentration are also reported.

关键词: cancer cell, matrigel, migration, shape deformation

Abstract:

Key words: cancer cell, matrigel, migration, shape deformation

中图分类号: (Cell processes)

87.17.-d

87.17.Jj (Cell locomotion, chemotaxis) 87.18.Ed (Cell aggregation) 05.40.Jc (Brownian motion)

叶腾, 邱峰. Influence of matrigel on the shape and dynamics of cancer cells[J]. 中国物理B, 2019, 28(10): 108704-108704.

Teng Ye(叶腾), Feng Qiu(邱峰). Influence of matrigel on the shape and dynamics of cancer cells[J]. Chin. Phys. B, 2019, 28(10): 108704-108704.

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Influence of matrigel on the shape and dynamics of cancer cells

Influence of matrigel on the shape and dynamics of cancer cells

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