Low-energy termination of spiral turbulence in heterogeneous myocardium using circularly polarized electric fields

doi:10.1088/1674-1056/ae24ee

中国物理B ›› 2026, Vol. 35 ›› Issue (3): 38201-038201.doi: 10.1088/1674-1056/ae24ee

Low-energy termination of spiral turbulence in heterogeneous myocardium using circularly polarized electric fields

Yu-Jie Lv(吕玉杰)¹, Xia Feng(冯霞)^1,†, Wan-Jie Mei(梅万杰)¹, Kai-Wen Sun(孙凯文)¹, Chun Zhang(张春)¹, and Xiang Gao(高翔)^2,‡

1 Faculty of Science, Xi'an Shiyou University, Xi'an 710065, China;
2 School of Physics and Information Technology, Shaanxi Normal University, Xi'an 710062, China

收稿日期:2025-09-14 修回日期:2025-11-08 接受日期:2025-11-27 发布日期:2026-02-12
通讯作者: Xia Feng, Xiang Gao E-mail:fengxia0709@126.com;gaoxiang.gnaixoag@gmail.com
基金资助:
Project supported by the National Natural Science Foundation of China (Grant No. 11647055), the Natural Science Basic Research Program of Shaanxi Province (Grant Nos. 2024JC-YBMS-073, 2024JC-YBMS-074, and 2023-JCQN-0013), the Scientific Research Program Funded by Shaanxi Provincial Education Department (Grant No. 23JK0604), and the National College Students Innovation and Entrepreneurship Training Program of Xi’an Shiyou University (Grant No. 202310705020).

Low-energy termination of spiral turbulence in heterogeneous myocardium using circularly polarized electric fields

Yu-Jie Lv(吕玉杰)¹, Xia Feng(冯霞)^1,†, Wan-Jie Mei(梅万杰)¹, Kai-Wen Sun(孙凯文)¹, Chun Zhang(张春)¹, and Xiang Gao(高翔)^2,‡

1 Faculty of Science, Xi'an Shiyou University, Xi'an 710065, China;
2 School of Physics and Information Technology, Shaanxi Normal University, Xi'an 710062, China

Received:2025-09-14 Revised:2025-11-08 Accepted:2025-11-27 Published:2026-02-12
Contact: Xia Feng, Xiang Gao E-mail:fengxia0709@126.com;gaoxiang.gnaixoag@gmail.com
Supported by:
Project supported by the National Natural Science Foundation of China (Grant No. 11647055), the Natural Science Basic Research Program of Shaanxi Province (Grant Nos. 2024JC-YBMS-073, 2024JC-YBMS-074, and 2023-JCQN-0013), the Scientific Research Program Funded by Shaanxi Provincial Education Department (Grant No. 23JK0604), and the National College Students Innovation and Entrepreneurship Training Program of Xi’an Shiyou University (Grant No. 202310705020).

摘要/Abstract

摘要： Circularly polarized electric fields (CPEF) represent a highly promising low-energy defibrillation approach, demonstrating exceptional efficacy in terminating life-threatening arrhythmias such as ventricular fibrillation while effectively mitigating the myocardial injury risks associated with conventional high-voltage defibrillation. This study provides an in-depth revelation of the mechanism by which CPEF induces excitation waves around naturally occurring heterogeneous defects within heart tissue, thereby suppressing spiral turbulence. Through numerical simulations based on the LR1 model and phase field method, we confirm that CPEF, due to its dynamic rotational properties, induces virtual electrode effects around various defects. In conditions of low strength, CPEF adaptively excites these defects, thereby achieving synchronized myocardial activation for defibrillation. In comparison with uniform electric fields (UEF), CPEF is more effective in suppressing spiral turbulence by inducing periodic excitation waves around defects with irregular geometries. These findings elucidate the biophysical principles underlying CPEF’s low-energy defibrillation capability, offering robust theoretical support for developing non-invasive antiarrhythmic therapies.

关键词: spiral, pattern formation, excitable system, virtual electrode

Abstract: Circularly polarized electric fields (CPEF) represent a highly promising low-energy defibrillation approach, demonstrating exceptional efficacy in terminating life-threatening arrhythmias such as ventricular fibrillation while effectively mitigating the myocardial injury risks associated with conventional high-voltage defibrillation. This study provides an in-depth revelation of the mechanism by which CPEF induces excitation waves around naturally occurring heterogeneous defects within heart tissue, thereby suppressing spiral turbulence. Through numerical simulations based on the LR1 model and phase field method, we confirm that CPEF, due to its dynamic rotational properties, induces virtual electrode effects around various defects. In conditions of low strength, CPEF adaptively excites these defects, thereby achieving synchronized myocardial activation for defibrillation. In comparison with uniform electric fields (UEF), CPEF is more effective in suppressing spiral turbulence by inducing periodic excitation waves around defects with irregular geometries. These findings elucidate the biophysical principles underlying CPEF’s low-energy defibrillation capability, offering robust theoretical support for developing non-invasive antiarrhythmic therapies.

Key words: spiral, pattern formation, excitable system, virtual electrode

中图分类号: (Pattern formation in reactions with diffusion, flow and heat transfer)

82.40.Ck

87.18.Hf (Spatiotemporal pattern formation in cellular populations) 87.19.lp (Pattern formation: activity and anatomic)

Yu-Jie Lv(吕玉杰), Xia Feng(冯霞), Wan-Jie Mei(梅万杰), Kai-Wen Sun(孙凯文), Chun Zhang(张春), and Xiang Gao(高翔). Low-energy termination of spiral turbulence in heterogeneous myocardium using circularly polarized electric fields[J]. 中国物理B, 2026, 35(3): 38201-038201.

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Low-energy termination of spiral turbulence in heterogeneous myocardium using circularly polarized electric fields

Low-energy termination of spiral turbulence in heterogeneous myocardium using circularly polarized electric fields

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