Magnetic nanoparticle-based cancer nanodiagnostics

doi:10.1088/1674-1056/22/5/058702

中国物理B ›› 2013, Vol. 22 ›› Issue (5): 58702-058702.doi: 10.1088/1674-1056/22/5/058702

所属专题： TOPICAL REVIEW — Magnetism, magnetic materials, and interdisciplinary research

• SPECIAL TOPIC --- Non-equilibrium phenomena in soft matters • 上一篇下一篇

Magnetic nanoparticle-based cancer nanodiagnostics

Muhammad Zubair Yousaf^a, 余靓^a, 侯仰龙^a, 高松^b

a Department of Materials Science and Engineering, College of Engineering, Peking University, Beijing 100871, China;
b College of Chemistry and Molecular Engineering, Peking University, Beijing 100871, China

收稿日期:2013-03-28 出版日期:2013-04-01 发布日期:2013-04-01
基金资助:
Project supported by the National Natural Science Foundation of China (Grant Nos. 51125001, 51172005, and 90922033), the Research Fellowship for International Young Scientists of the National Natural Science Foundation of China (Grant No. 51250110078), the Doctoral Program of the Education Ministry of China (Grant No. 20120001110078), and the PKU COE-Health Science Center Seed Fund, China.

Magnetic nanoparticle-based cancer nanodiagnostics

Muhammad Zubair Yousaf^a, Yu Jing (余靓)^a, Hou Yang-Long (侯仰龙)^a, Gao Song (高松)^b

a Department of Materials Science and Engineering, College of Engineering, Peking University, Beijing 100871, China;
b College of Chemistry and Molecular Engineering, Peking University, Beijing 100871, China

Received:2013-03-28 Online:2013-04-01 Published:2013-04-01
Contact: Hou Yang-Long E-mail:hou@pku.edu.cn
Supported by:
Project supported by the National Natural Science Foundation of China (Grant Nos. 51125001, 51172005, and 90922033), the Research Fellowship for International Young Scientists of the National Natural Science Foundation of China (Grant No. 51250110078), the Doctoral Program of the Education Ministry of China (Grant No. 20120001110078), and the PKU COE-Health Science Center Seed Fund, China.

摘要/Abstract

摘要： Diagnosis facilitates the discovery of an impending disease. A complete and accurate treatment of cancer depends heavily on its early medical diagnosis. Cancer, one of the most fatal diseases world-wide, consistently affects a larger number of patients each year. Magnetism, a physical property arising from the motion of electrical charges, which causes attraction and repulsion between objects and does not involve radiation, has been under intense investigation for several years. Magnetic materials show great promise in the application of image contrast enhancement to accurately image and diagnose cancer. Chelating gadolinium (Gd III) and magnetic nanoparticles (MNPs) have the prospect to pave the way for diagnosis, operative management, and adjuvant therapy of different kinds of cancers. The potential of MNP-based magnetic resonance (MR) contrast agents (CAs) now makes it possible to image portions of a tumor in parts of the body that would be unclear with the conventional magnetic resonance imaging (MRI). Multiple functionalities like variety of targeting ligands and image contrast enhancement have recently been added to the MNPs. Keeping aside the additional complexities in synthetic steps, costs, more convoluted behavior, and effects in-vivo, multifunctional MNPs still face great regulatory hurdles before clinical availability for cancer patients. The trade-off between additional functionality and complexity is a subject of ongoing debate. The recent progress regarding the types, design, synthesis, morphology, characterization, modification, and the in-vivo and in-vitro uses of different MRI contrast agents, including MNPs, to diagnose cancer will be the focus of this review. As our knowledge of MNPs’ characteristics and applications expands, their role in the future management of cancer patients will become very important. Current hurdles are also discussed, along with future prospects of MNPs as the savior of cancer victims.

关键词: cancer, magnetic nanoparticle, magnetism, diagnosis, nanotechnology

Abstract: Diagnosis facilitates the discovery of an impending disease. A complete and accurate treatment of cancer depends heavily on its early medical diagnosis. Cancer, one of the most fatal diseases world-wide, consistently affects a larger number of patients each year. Magnetism, a physical property arising from the motion of electrical charges, which causes attraction and repulsion between objects and does not involve radiation, has been under intense investigation for several years. Magnetic materials show great promise in the application of image contrast enhancement to accurately image and diagnose cancer. Chelating gadolinium (Gd III) and magnetic nanoparticles (MNPs) have the prospect to pave the way for diagnosis, operative management, and adjuvant therapy of different kinds of cancers. The potential of MNP-based magnetic resonance (MR) contrast agents (CAs) now makes it possible to image portions of a tumor in parts of the body that would be unclear with the conventional magnetic resonance imaging (MRI). Multiple functionalities like variety of targeting ligands and image contrast enhancement have recently been added to the MNPs. Keeping aside the additional complexities in synthetic steps, costs, more convoluted behavior, and effects in-vivo, multifunctional MNPs still face great regulatory hurdles before clinical availability for cancer patients. The trade-off between additional functionality and complexity is a subject of ongoing debate. The recent progress regarding the types, design, synthesis, morphology, characterization, modification, and the in-vivo and in-vitro uses of different MRI contrast agents, including MNPs, to diagnose cancer will be the focus of this review. As our knowledge of MNPs’ characteristics and applications expands, their role in the future management of cancer patients will become very important. Current hurdles are also discussed, along with future prospects of MNPs as the savior of cancer victims.

Key words: cancer, magnetic nanoparticle, magnetism, diagnosis, nanotechnology

中图分类号: (Cancer)

87.19.xj

87.57.-s (Medical imaging) 87.61.-c (Magnetic resonance imaging) 87.85.-d (Biomedical engineering)

Muhammad Zubair Yousaf, 余靓, 侯仰龙, 高松. Magnetic nanoparticle-based cancer nanodiagnostics[J]. 中国物理B, 2013, 22(5): 58702-058702.

Muhammad Zubair Yousaf, Yu Jing (余靓), Hou Yang-Long (侯仰龙), Gao Song (高松). Magnetic nanoparticle-based cancer nanodiagnostics[J]. Chin. Phys. B, 2013, 22(5): 58702-058702.

参考文献 170

[1]	ten Tije A J, Verweij J, Loos W J and Sparreboom A 2003 Clin. Pharmacokinet.42 665
[2]	Walko C M and Lindley C 2005 Clin. Ther. 27 23
[3]	Azzazy H M, Mansour M M and Kazmierczak S C 2006 Clin. Chem.52 1238
[4]	Jain K K 2007 Clin. Chem. 53 2002
[5]	Lee W G, Kim Y G, Chung B G, Demirci U and Khademhosseini A2010 Adv. Drug. Deliv. Rev. 62 449
[6]	Tallury P, Malhotra A, Byrne L M and Santra S 2010 Adv. Drug. Deliv.Rev. 62 424
[7]	Gao J, Gu H and Xu B 2009 Accounts Chem. Res. 42 1097
[8]	Aime S, Castelli D D, Crich S G, Gianolio E and Terreno E 2009 AccountsChem. Res. 42 822
[9]	Aime S, DastruW, Crich S G, Gianolio E and Mainero V 2002 Biopolymers66 419
[10]	Caravan P, Ellison J J, McMurry T J and Lauffer R B 1999 Chem. Rev.99 2293
[11]	Revett K 2011 Innovations in Intelligent Image Analysis (Berlin:Springer-Verlag) p. 127
[12]	Pankhurst Q A, Connolly J, Jones S K and Dobson J 2003 J. Phys. DAppl. Phys. 36 R167
[13]	Gun’ko Y K and Brougham D F 2007 Nanotechnologies for the LifeSciences (Baton Rouge: Wiley-VCH) p. 3
[14]	Gang H and Bin H 2012 Appl. Phys. Lett. 100 013704
[15]	Na H B, Song I C and Hyeon T 2009 Adv. Mater. 21 2133
[16]	Perez J M, Josephson L and Weissleder R 2004 Chem. Bio. Chem. 5261
[17]	Corot C, Robert P, Idee J M and Port M 2006 Adv. Drug. Deliv. Rev. 581471
[18]	Gupta A K and Gupta M 2005 Biomaterials 26 3995
[19]	Harisinghani M G, Barentsz J, Hahn P F, Deserno W M, Tabatabaei S,van de Kaa C H, de la Rosette J andWeissleder R 2003 N. Engl. J. Med.348 2491
[20]	Huh Y M, Jun Y W, Song H T, Kim S, Choi J S, Lee J H, Yoon S, KimK S, Shin J S, Suh J S and Cheon J 2005 J. Am. Chem. Soc. 127 12387
[21]	Ito A, Shinkai M, Honda H and Kobayashi T 2005 J. Biosci. Bioeng.100 1
[22]	Lee J H, Huh Y M, Jun Y W, Seo J W, Jang J T, Song H T, Kim S, ChoE J, Yoon H G, Suh J S and Cheon J 2007 Nat. Med. 13 95
[23]	Mornet S, Vasseur S, Grasset F and Duguet E 2004 J. Mater. Chem. 142161
[24]	Neuberger T, Schopf B, Hofmann H, Hofmann M and von RechenbergB 2005 J. Magn. Magn. Mater. 293 483
[25]	Sun C, Lee J S H and Zhang M 2008 Adv. Drug. Deliv. Rev. 60 1252
[26]	Gupta A K, Naregalkar R R, Vaidya V D and Gupta M 2007Nanomedicine 2 23
[27]	Laurent S, Forge D, Port M, Roch A, Robic C, Elst L V and Muller RN 2008 Chem. Rev. 108 2064
[28]	Geraldes C F G C and Laurent S 2009 Contrast Media. Mol. Imaging4 1
[29]	Ruoslahti E, Bhatia S N and Sailor M J 2010 J. Cell Biol. 188 759
[30]	Penfield J G and Reilly R F Jr 2007 Nat. Clin. Pract. Nephrol. 3 654
[31]	Zhou Z and Lu Z R 2013 Wiley Interdiscip. Rev. Nanomed.Nanobiotechnol. 5 1
[32]	Altun E, Semelka R C and Cakit C 2009 Acad. Radiol. 16 897
[33]	Kay J 2008 Ann. Rheum. Dis. 67 66
[34]	Sharrna P, Brown S, Walter G, Santra S and Moudgil B 2006 Adv. ColloidInterface Sci. 123 471
[35]	Burkhard P 2006 Nanomed. Nanotechnol. Biol. Med. 2 95
[36]	Debouttiere P J, Roux S, Vocanson F, Billotey C, Beuf O, Favre-Reguillon A, Lin Y, Pellet-Rostaing S, Lamartine R, Perriat P and TillementO 2006 Adv. Funct. Mater. 16 2330
[37]	Cheng Y C, Chiang C M, Wu C C and Chai J W 2012 J. Chin. Med.Assoc. 75 355
[38]	Denecke T, Steffen I G, Agarwal S, Seehofer D, Kroencke T, HaenninenE L, Kramme I B, Neuhaus P, Saini S, Hamm B and Grieser C2012 Eur. Radiol. 22 1769
[39]	Kamaly N, Kalber T, Thanou M, Bell J D and Miller A D 2009 BioconjugateChem. 20 648
[40]	Santra S, Jativa S D, Kaittanis C, Normand G, Grimm J and Perez J M2012 ACS Nano 6 7281
[41]	Rhee H, Kim M J, Park M S and Kim K A 2012 Br. J. Radiol. 85 E837
[42]	Fries P, Runge V M, Buecker A, Schuerholz H, Reith W, Robert P,Jackson C, Lanz T and Schneider G 2009 Invest. Radiol. 44 200
[43]	Port M, Corot C, Rousseaux O, Raynal I, Devoldere L, Idee J M, DencausseA, Le Greneur S, Simonot C and Meyer D 2001 Magn. Reson.Mat. Phys. Biol. Med. 12 121
[44]	Daldrup H, Shames D M,Wendland M, Okuhata Y, Link T M, RosenauW, Lu Y and Brasch R C 1998 Pediatr. Radiol. 28 67
[45]	Ogan M D, Schmiedl U, Moseley M E, Grodd W, Paajanen H andBrasch R C 1987 Invest. Radiol. 22 665
[46]	Schmiedl U, Ogan M, Paajanen H, Marotti M, Crooks L E, Brito A Cand Brasch R C 1987 Radiology 162 205
[47]	Raatschen H J, Simon G H, Fu Y, Sennino B, Shames D M, WendlandM F, McDonald D M and Brasch R C 2008 Radiology 247 391
[48]	Dafni H, Kim S J, Bankson J A, Sankaranaravanapillai M and Ronen SM 2008 Magn. Reson. Med. 60 822
[49]	Bhujwalla Z M, Artemov D, Natarajan K, Solaiyappan M, Kollars Pand Kristjansen P E G 2003 Clin. Cancer Res. 9 355
[50]	Schuhmanngiampieri G, Schmittwillich H, Frenzel T, Press W R andWeinmann H J 1991 Invest. Radiol. 26 969
[51]	Curtet C, Maton F, Havet T, Slinkin M, Mishra A, Chatal J F and MullerR N 1998 Invest. Radiol. 33 752
[52]	Adam G, Neuerburg J, Spuntrup E, Muhler A, Scherer K and GuntherR W 1994 J. Magn. Reson. Imaging 4 462
[53]	Wang S C, Wikstrom M G, White D L, Klaveness J, Holtz E, RongvedP, Moseley M E and Brasch R C 1990 Radiology 175 483
[54]	Rebizak R, Schaefer M and Dellacherie E 1998 Bioconjugate Chem. 994
[55]	Venditto V J, Regino C A S and Brechbiel M W 2005 Mol. Pharm. 2302
[56]	Wiener E C, Brechbiel M W, Brothers H, Magin R L, Gansow O A,Tomalia D A and Lauterbur P C 1994 Magn. Reson. Med. 31 1
[57]	Langereis S, de Lussanet Q G, van Genderen M H P, Backes W H andMeijer E W 2004 Macromolecules 37 3084
[58]	Langereis S, de Lussanet Q G, van GenderenMH P, Meijer EW, Beets-Tan R G H, Griffioen A W, van Engelshoven J M A and Backes W H2006 NMR Biomed. 19 133
[59]	Kobayashi H and Brechbiel MW2004 Curr. Pharm. Biotechnol. 5 539
[60]	Kobayashi H and Brechbiel M W 2005 Adv. Drug. Deliv. Rev. 57 2271
[61]	Luo K, Liu G, She W C, Wang Q Y, Wang G, He B, Ai H, Gong Q Y,Song B and Gu Z W 2011 Biomaterials 32 7951
[62]	Storrs R W, Tropper F D, Li H Y, Song C K, Kuniyoshi J K, Sipkins DA, Li K C P and Bednarski M D 1995 J. Am. Chem. Soc. 117 7301
[63]	Kaneshiro T L, Ke T, Jeong E K, Parker D L and Lu Z R 2006 Pharm.Res. 23 1285
[64]	Lu Z R, Mohs A M, Zong Y and Feng Y 2006 Int. J. Nanomed. 1 31
[65]	Lu Z R and Wu X M 2010 Isr. J. Chem. 50 220
[66]	Zong Y D, Wang X L, Jeong E K, Parker D L and Lu Z R 2009 Magn.Reson. Imaging 27 503
[67]	Mayer L D, Masin D, Nayar R, Boman N L and Bally M B 1995 Br. J.Cancer 71 482
[68]	Papahadjopoulos D, Allen T M, Gabizon A, Mayhew E, Matthay K,Huang S K, Lee K D, Woodle M C, Lasic D D, Redemann C and MartinF J 1991 Proc. Natl. Acad. Sci. USA 88 11460
[69]	Unger E C, Macdougall P, Cullis P and Tilcock C 1989 Magn. Reson.Imaging 7 417
[70]	Krauze M T, Forsayeth J, Park J W and Bankiewicz K S 2006 Pharm.Res. 23 2493
[71]	Mamot C, Nguyen J B, Pourdehnad M, Hadaczek P, Saito R, Bringas JR, Drummond D C, Hong K L, Kirpotin D B, McKnight T, Berger MS, Park J W and Bankiewicz K S 2004 J. Neuro-Oncol. 68 1
[72]	Karathanasis E, Park J, Agarwal A, Patel V, Zhao F, Annapragada A V,Hu X and Bellamkonda R V 2008 Nanotechnology 19 315101
[73]	Ghaghada K B, Ravoori M, Sabapathy D, Bankson J, Kundra V andAnnapragada A 2009 Plos One 4 e7628
[74]	Park J A, Lee J J, Jung J C, Yu D Y, Oh C, Ha S, Kim T J and Chang YM 2008 Chem. Bio. Chem. 9 2811
[75]	Pilch J, Brown D M, Komatsu M, Jarvinen T A H, Yang M, Peters D,Hoffman R M and Ruoslahti E 2006 Proc. Natl. Acad. Sci. USA 1032800
[76]	Artemov D 2003 J. Cell. Biochem. 90 518
[77]	Artemov D, Mori N, Ravi R and Bhujwalla Z M 2003 Cancer Res. 632723
[78]	ShazeebMS, Sotak C H, DeLeoMand Bogdanov A 2011 Cancer Res.71 2230
[79]	Xu H, Regino C A S, Koyama Y, Hama Y, Gunn A J, Bernardo M,Kobayashi H, Choyke P L and Brechbiel M W 2007 BioconjugateChem. 18 1474
[80]	ZhuWL, Mollie B, Bhujwalla ZMand Artemov D 2008 Magn. Reson.Med. 59 679
[81]	Huang R Q, Han L, Li J F, Liu S H, Shao K, Kuang Y Y, Hu X, WangX X, Lei H and Jiang C 2011 Biomaterials 32 5177
[82]	Han L A, Li J F, Huang S X, Huang R Q, Liu S H, Hu X, Yi P W, ShanD, Wang X X, Lei H and Jiang C 2011 Biomaterials 32 2989
[83]	Swanson S D, Kukowska-Latallo J F, Patri A K, Chen C Y, Ge S, CaoZ Y, Kotlyar A, East A T and Baker J R 2008 Int. J. Nanomed. 3 201
[84]	Reddy J A, Xu L C, Parker N, Vetzel M and Leamon C P 2004 J. Nucl.Med. 45 857
[85]	Parker N, Turk M J, Westrick E, Lewis J D, Low P S and Leamon C P2005 Anal. Biochem. 338 284
[86]	Sipkins D A, Cheresh D A, Kazemi M R, Nevin L M, Bednarski M Dand Li K C P 1998 Nat. Med. 4 623
[87]	Vaccaro M, Accardo A, D’Errico G, Schillen K, Radulescu A, TesauroD, Morelli G and Paduano L 2007 Biophys. J. 93 1736
[88]	Accardo A, Tesauro D, Roscigno P, Gianolio E, Paduano L, D’ErricoG, Pedone C and Morelli G 2004 J. Am. Chem. Soc. 126 3097
[89]	Cho H J, Yoon H Y, Koo H, Ko S H, Shim J S, Cho J H, Park J H, KimK, Kwon I C and Kim D D 2012 J. Control. Release 162 111
[90]	Wu X M, Burden-Gulley S M, Yu G P, Tan M Q, Lindner D, Brady-Kalnay S M and Lu Z R 2012 Bioconjugate Chem. 23 1548
[91]	Faucher L, Tremblay M, Lagueux J, Gossuin Y and Fortin M A 2012ACS Appl. Mater. Interfaces 4 4506
[92]	Arpaci T, Ugurluer G, Akbas T, Arpaci R B and SerinM2012 Eur. Rev.Med. Pharmacol. Sci. 16 2057
[93]	Koh T S, Hartono S, Thng C H, Lim T K H, Martarello L and Ng Q S2013 Magn. Reson. Med. 69 269
[94]	Chow A M, Tan M, Gao D S, Fan S J, Cheung J S, Qiao Z, Man K, LuZ R and Wu E X 2013 Invest. Radiol. 48 46
[95]	Frullano L and Caravan P 2011 Curr. Org. Synth. 8 535
[96]	Qiao R, Yang C and Gao M 2009 J. Mater. Chem. 19 6274
[97]	Cengelli F, Maysinger D, Tschudi-Monnet F, Montet X, Corot C, Petri-Fink A, Hofmann H and Juillerat-Jeanneret L 2006 J. Pharmacol. Exp.Ther. 318 108
[98]	Kim D K, Mikhaylova M, Wang F H, Kehr J, Bjelke B, Zhang Y,Tsakalakos T and Muhammed M 2003 Chem. Mat. 15 4343
[99]	Lee H, Lee E, Kim D K, Jang N K, Jeong Y Y and Jon S 2006 J. Am.Chem. Soc. 128 7383
[100]	Leuschner C, Kumar C S S R, Hansel W, Soboyejo W, Zhou J andHormes J 2006 Breast Cancer Res. Treat. 99 163
[101]	Ma H l, Qi X T, Maitani Y and Nagai T 2007 Int. J. Pharm. 333 177
[102]	Mahmoudi M, Simchi A and ImaniM2009 J. Phys. Chem. C 113 9573
[103]	Pawelczyk E, Arbab A S, Chaudhry A, Balakumaran A, Robey P Gand Frank J A 2008 Stem Cells. 26 1366
[104]	Talelli M, Rijcken C J F, Lammers T, Seevinck P R, Storm G, van NostrumC F and Hennink W E 2009 Langmuir 25 2060
[105]	Tong S, Hou S, Zheng Z, Zhou J and Bao G 2010 Nano Lett. 10 4607
[106]	Nunn A VW, BarnardML, Bhakoo K, Murray J, Chilvers E J and BellJ D 1996 FEBS Lett. 392 295
[107]	Nakamura H, Ito N, Kotake F, Mizokami Y and Matsuoka T 2000 J.Gastroenterol. 35 849
[108]	Inoue T, Kudo M, Watai R, Pei Z, Kawasaki T, Minami Y, Chung H,Fukunaga T, Awai K and Maenishi O 2005 J. Gastroenterol. 40 1139
[109]	Lee N, Choi Y, Lee Y, Park M, Moon W K, Choi S H and Hyeon T2012 Nano Lett. 12 3127
[110]	Bonnemain B 1998 J. Drug Target. 6 167
[111]	Wang Y X J, Hussain S M and Krestin G P 2001 Eur. Radiol. 11 2319
[112]	Reimer P, Jahnke N, Fiebich M, Schima W, Deckers F, Marx C,Holzknecht N and Saini S 2000 Radiology 217 152
[113]	Ros P R, Freeny P C, Harms S E, Seltzer S E, Davis P L, Chan T W,Stillman A E, Muroff L R, Runge V M, Nissenbaum M A and JacobsP M 1995 Radiology 196 481
[114]	Neuwelt E A, Hamilton B E, Varallyay C G, Rooney W R, Edelman RD, Jacobs P M and Watnick S G 2009 Kidney Int. 75 465
[115]	Ba-Ssalamah A, Uffmann M, Saini S, Bastati N, Herold C and SchimaW 2009 Eur. Radiol. 19 342
[116]	Blankenberg F G, Katsikis P D, Storrs R W, Beaulieu C, Spielman D,Chen J Y, Naumovski L and Tait J F 1997 Blood 89 3778
[117]	Mahajan S, Koul V, Choudhary V, Shishodia G and Bharti A C 2013Nanotechnology 24
[118]	Jae Yeon P, Hyuck Jae C, Gi-Eun N, Kyoung-Sik C and Joo-Hiuk S2012 IEEE Trans. Tera. Sci. Technol. 2 93
[119]	Mergo P J, Engelken J D, Helmberger T and Ros P R 1998 J. Magn.Reson. Imaging 8 1073
[120]	Bumb A, Brechbiel M W, Choyke P L, Fugger L, Eggeman A, PrabhakaranD, Hutchinson J and Dobson P J 2008 Nanotechnology 19
[121]	Jiang T, Zhang C, Zheng X, Xu X, Xie X, Liu H and Liu S 2009 Int. J.Nanomed. 4 241
[122]	Li M, Kim H S, Tian L, Yu M K, Jon S and Moon W K 2012 Theranostics2 76
[123]	Tetsumura A, Nakamura S, Yoshino N, Watanabe H, Kuribayashi A,Nagumo K, Okada N, Sasaki T and Kurabayashi T 2012 Dentomaxillofac.Radiol. 41 55
[124]	Yang H M, Lee H J, Jang K S, Park C W, Yang H W, Do Heo W andKim J D 2009 J. Mater. Chem. 19 4566
[125]	Aime S and Caravan P 2009 J. Magn. Reson. Imaging 30 1259
[126]	Kribben A, Witzke O, Hillen U, Barkhausen J, Daul A E and Erbel R2009 J. Am. Coll. Cardiol. 53 1621
[127]	Kuo P H 2008 J. Am. Coll. Radiol. 5 29
[128]	Lee J H and Koretsky A P 2004 Curr. Pharm. Biotechnol. 5 529
[129]	Silva A C, Lee J H, Aoki L and Koretsky A R 2004 NMR Biomed. 17532
[130]	Bertin A, Steibel J, Michou-Gallani A I, Gallani J L and Felder-FleschD 2009 Bioconjugate Chem. 20 760
[131]	Pan D, Caruthers S D, Hu G, Senpan A, Scott M J, Gaffney P J, WicklineS A and Lanza G M 2008 J. Am. Chem. Soc. 130 9186
[132]	Pan D P J, Senpan A, Caruthers S D,Williams T A, Scott M J, GaffneyP J, Wickline S A and Lanza G M 2009 Chem. Commun. 3234
[133]	Tan M Q, Ye Z, Jeong E K, Wu X M, Parker D L and Lu Z R 2011Bioconjugate Chem. 22 931
[134]	Zhen Y, Eun-Kee J, Xueming W, Mingqian T, Shouyu Y and Zheng-Rong L 2012 J. Magn. Reson. Imaging 35 737
[135]	Lu Z R, Parker D L, Goodrich K C, Wang X H, Dalle J G and BuswellH R 2004 Magn. Reson. Med. 51 27
[136]	Zong Y, Guo J, Ke T, Mohs A M, Parker D L and Lu Z R 2006 J.Control. Release. 112 350
[137]	Feng Y, Zong Y D, Ke T Y, Jeong E K, Parker D L and Lu Z R 2006Pharm. Res. 23 1736
[138]	Braun R D, Bissig D, North R, Vistisen K S and Berkowitz B A 2012Plos One 7
[139]	Mouraviev V, Venkatraman T N, Tovmasyan A, Kimura M, Tsivian M,Mouravieva V, Polascik T J, Wang H, Amrhein T J, Batinic-Haberle Iand Lascola C 2012 J. Endourol. 26 1420
[140]	L′etourneau M, Tremblay M, Faucher L, Rojas D, Chevallier P, GossuinY, Lagueux J and Fortin M A 2012 J. Phys. Chem. B 116 13228
[141]	WarsiMF, Adams RW, Duckett S B and Chechik V 2010 Chem. Commun.46 451
[142]	Endres P J, Paunesku T, Vogt S, Meade T J and Woloschak G E 2007J. Am. Chem. Soc. 129 15760
[143]	Na H B, Lee J H, An K, Park Y I, Park M, Lee I S, Nam D H, Kim S T,Kim S H, Kim S W, Lim K H, Kim K S, Kim S O and Hyeon T 2007Angew. Chem. Int. Ed. 46 5397
[144]	Su C H, Sheu H S, Lin C Y, Huang C C, Lo Y W, Pu Y C, Weng J C,Shieh D B, Chen J H and Yeh C S 2007 J. Am. Chem. Soc. 129 2139
[145]	Joshi R, Feldmann V, Koestner W, Detje C, Gottschalk S, Mayer H A,Sauer M G and Engelmann J 2013 Biol. Chem. 394 125
[146]	Sterenczak K A, Meier M, Glage S, Meyer M, Willenbrock S, WefstaedtP, Dorsch M, Bullerdiek J, Escobar H M, Hedrich H and Nolte I2012 Bmc Cancer 12
[147]	Ling Y, Wei K, Zou F and Zhong S 2012 Int. J. Pharm. 430 266
[148]	Shao H, Yoon T J, Liong M, Weissleder R and Lee H 2010 Beilstein JNanotechnol 1 142
[149]	Fan H M, Olivo M, Shuter B, Yi J B, Bhuvaneswari R, Tan H R, XingG C, Ng C T, Liu L, Lucky S S, Bay B H and Ding J 2010 J. Am. Chem.Soc. 132 14803
[150]	Cheon J and Lee J H 2008 Accounts Chem. Res. 41 1630
[151]	Tallury P, Payton K and Santra S 2008 Nanomedicine 3 579
[152]	Gu H W, Zheng R K, Zhang X X and Xu B 2004 J. Am. Chem. Soc.126 5664
[153]	Gao J H, Zhang B, Gao Y, Pan Y, Zhang X X and Xu B 2007 J. Am.Chem. Soc. 129 11928
[154]	Lim E K, Yang J, Dinney C P N, Suh J S, Huh Y M and Haam S 2010Biomaterials 31 9310
[155]	Selvan S T, Patra P K, Ang C Y and Ying J Y 2007 Angew. Chem. Int.Ed. 46 2448
[156]	Yang Y M, Aw J X, Chen K, Liu F, Padmanabhan P, Hou Y L, ChengZ and Xing B G 2011 Chem. Asian J. 6 1381
[157]	Park J H, von Maltzahn G, Ruoslahti E, Bhatia S N and Sailor M J2008 Angew. Chem. Int. Ed. 47 7284
[158]	Gao J H, Zhang W, Huang P B, Zhang B, Zhang X X and Xu B 2008J. Am. Chem. Soc. 130 3710
[159]	Xu C, Xie J, Ho D, Wang C, Kohler N, Walsh E G, Morgan J R, ChinY E and Sun S 2008 Angew. Chem. Int. Ed. 47 173
[160]	Gu HW, Yang Z M, Gao J H, Chang C K and Xu B 2005 J. Am. Chem.Soc. 127 34
[161]	Jiang J, Gu H, Shao H, Devlin E, Papaefthymiou G C and Ying J Y2008 Adv. Mater. 20 4403
[162]	Xie J, Zhang F, Aronova M, Zhu L, Lin X, Quan Q, Liu G, Zhang G,Choi K Y, Kim K, Sun X, Lee S, Sun S, Leapman R and Chen X 2011ACS Nano 5 3043
[163]	Reddy G R, Bhojani M S, McConville P, Moody J, Moffat B A, HallD E, Kim G, Koo Y E L, Woolliscroft M J, Sugai J V, Johnson T D,Philbert M A, Kopelman R, Rehemtulla A and Ross B D 2006 Clin.Cancer Res. 12 6677
[164]	Grootendorst D J, Jose J, Fratila R M, Visscher M, Velders A H, TenHaken B, Van Leeuwen T G, Steenbergen W, Manohar S and Ruers TJ M 2013 Contrast Media Mol. Imaging 8 83
[165]	O’Grady K 2009 J. Phys. D: Appl. Phys. 42 224001
[166]	Berry C C 2009 J. Phys. D: Appl. Phys. 42 224003
[167]	Roca A G, Costo R, Rebolledo A F, Veintemillas-Verdaguer S, TartajP, Gonzalez-Carreno T, Morales M P and Serna C J 2009 J. Phys. D:Appl. Phys. 42 224002
[168]	Wang S X, Zhou Y and Sun W T 2009 Materials Science & EngineeringC-Biomimetic and Supramolecular Systems 29 1196
[169]	Berry C C and Curtis A S G 2003 J. Phys. D: Appl. Phys. 36 R198
[170]	Tartaj P, Morales M D, Veintemillas-Verdaguer S, Gonzalez-Carreno Tand Serna C J 2003 J. Phys. D: Appl. Phys. 36 R182

Magnetic nanoparticle-based cancer nanodiagnostics

Magnetic nanoparticle-based cancer nanodiagnostics

PDF (PC)

赞

可视化

摘要/Abstract

引用本文

使用本文

参考文献 170

相关文章 15

Metrics

本文评价

推荐阅读 0

[1]	Wenyu Xiang(相文雨), Yaping Wang(王亚萍), Weixiao Ji(纪维霄), Wenjie Hou(侯文杰),Shengshi Li(李胜世), and Peiji Wang(王培吉). Prediction of one-dimensional CrN nanostructure as a promising ferromagnetic half-metal[J]. 中国物理B, 2023, 32(3): 37103-037103.
[2]	Ming Yan(闫明), Zhi-Yuan Xie(谢志远), and Miao Gao(高淼). High-temperature ferromagnetism and strong π-conjugation feature in two-dimensional manganese tetranitride[J]. 中国物理B, 2023, 32(3): 37104-037104.
[3]	Jia Chen(陈佳), Peiyue Yu(于沛玥), Lei Zhao(赵磊), Yanru Li(李彦如), Meiyin Yang(杨美音), Jing Xu(许静), Jianfeng Gao(高建峰), Weibing Liu(刘卫兵), Junfeng Li(李俊峰), Wenwu Wang(王文武), Jin Kang(康劲), Weihai Bu(卜伟海), Kai Zheng(郑凯), Bingjun Yang(杨秉君), Lei Yue(岳磊), Chao Zuo(左超), Yan Cui(崔岩), and Jun Luo(罗军). Charge-mediated voltage modulation of magnetism in Hf_0.5Zr_0.5O₂/Co multiferroic heterojunction[J]. 中国物理B, 2023, 32(2): 27504-027504.
[4]	Zhongchong Lin(林中冲), Yuxuan Peng(彭宇轩), Baochun Wu(吴葆春), Changsheng Wang(王常生), Zhaochu Luo(罗昭初), and Jinbo Yang(杨金波). Magnetic van der Waals materials: Synthesis, structure, magnetism, and their potential applications[J]. 中国物理B, 2022, 31(8): 87506-087506.
[5]	Zhong-Xue Huang(黄忠学), Rui Wang(王瑞), Xin Yang(杨鑫), Hao-Feng Chen(陈浩锋), and Li-Xin Cao(曹立新). Magnetic properties of oxides and silicon single crystals[J]. 中国物理B, 2022, 31(8): 87501-087501.
[6]	Chuchu Zhu(朱楚楚), Hao Su(苏豪), Erjian Cheng(程二建), Lin Guo(郭琳), Binglin Pan(泮炳霖), Yeyu Huang(黄烨煜), Jiamin Ni(倪佳敏), Yanfeng Guo(郭艳峰), Xiaofan Yang(杨小帆), and Shiyan Li(李世燕). High-pressure study of topological semimetals XCd₂Sb₂ (X = Eu and Yb)[J]. 中国物理B, 2022, 31(7): 76201-076201.
[7]	Jun Ren(任军), Junming Li(李军明), Sheng Zhang(张胜), Jun Li(李骏), Wenxia Su(苏文霞), Dunhui Wang(王敦辉), Qingqi Cao(曹庆琪), and Youwei Du(都有为). Voltage control magnetism and ferromagnetic resonance in an Fe₁₉Ni₈₁/PMN-PT heterostructure by strain[J]. 中国物理B, 2022, 31(7): 77502-077502.
[8]	Ning Xi(西宁) and Rong Yu(俞榕). Dynamical signatures of the one-dimensional deconfined quantum critical point[J]. 中国物理B, 2022, 31(5): 57501-057501.
[9]	Zhang Wen(文章), Xian-Qi Lin(林先其), Chen-Nan Li(李晨楠), and Yu-Lu Fan(樊钰璐). A low-cost invasive microwave ablation antenna with a directional heating pattern[J]. 中国物理B, 2022, 31(3): 38401-038401.
[10]	Guoqiang Li(李国强), Yanping Liu(刘艳平), Jingru Yao(姚静如), Kena Song(宋克纳), Gao Wang(王高), Lianjie Zhou(周连杰), Guo Chen(陈果), and Liyu Liu(刘雳宇). Biophysical model for high-throughput tumor and epithelial cell co-culture in complex biochemical microenvironments[J]. 中国物理B, 2022, 31(2): 28703-028703.
[11]	Boyi Li(李博艺), Chengcheng Liu(刘成成), Xin Liu(刘欣), Tho N. H. T. Tran, Ying Li(李颖), Dan Li(李旦), Dongsheng Bi(毕东生), Duwei Liu(刘度为), and Dean Ta(他得安). Amplitude modulation excitation for cancellous bone evaluation using a portable ultrasonic backscatter instrumentation[J]. 中国物理B, 2022, 31(11): 114303-114303.
[12]	Guangyi Chen(陈光毅), Yu Zhang(张玉), Shaomian Qi(齐少勉), and Jian-Hao Chen(陈剑豪). Gate-controlled magnetic transitions in Fe₃GeTe₂ with lithium ion conducting glass substrate[J]. 中国物理B, 2021, 30(9): 97504-097504.
[13]	Feng-Chun Pan(潘凤春), Xue-Ling Lin(林雪玲), and Xu-Ming Wang(王旭明). Strain-tuned magnetic properties in (Ga,Fe)Sb: First-principles study[J]. 中国物理B, 2021, 30(9): 96105-096105.
[14]	Wei Shen(沈威), Yuanhui Pan(潘远辉), Shengnan Shen(申胜男), Hui Li(李辉), Siyuan Nie(聂思媛), and Jie Mei(梅杰). Intrinsic two-dimensional multiferroicity in CrNCl₂ monolayer[J]. 中国物理B, 2021, 30(11): 117503-117503.
[15]	Fei Ding(丁飞), Yongxiang Ma(马雍翔), Xiangnan Gong(公祥南), Die Hu(胡蝶), Jun Zhao(赵俊), Lingli Li(李玲丽), Hui Zheng(郑慧), Yao Zhang(张耀), Yongjiang Yu(于永江), Lichun Zhang(张立春), Fengzhou Zhao(赵风周), and Bingying Pan(泮丙营). Structure and frustrated magnetism of the two-dimensional triangular lattice antiferromagnet Na₂BaNi(PO₄)₂[J]. 中国物理B, 2021, 30(11): 117505-117505.