Effect of magnetic field on expansion of ferrofluid-encapsulated microbubble

doi:10.1088/1674-1056/acc1d2

中国物理B ›› 2023, Vol. 32 ›› Issue (6): 64302-064302.doi: 10.1088/1674-1056/acc1d2

Effect of magnetic field on expansion of ferrofluid-encapsulated microbubble

Zhiwei Du(杜芷玮), Fan Li(李凡), Ruiqi Pan(潘瑞琪), Runyang Mo(莫润阳)^†, and Chenghui Wang(王成会)

Shaanxi Key Laboratory of Ultrasonics, Shaanxi Normal University, Xi'an 710119, China

收稿日期:2022-11-16 修回日期:2023-02-19 接受日期:2023-03-07 出版日期:2023-05-17 发布日期:2023-06-07
通讯作者: Runyang Mo E-mail:mmrryycn@snnu.edu.cn
基金资助:
Project supported by the National Natural Science Foundation of China (Grant Nos. 12074238, 11974232, and 11774212).

Effect of magnetic field on expansion of ferrofluid-encapsulated microbubble

Zhiwei Du(杜芷玮), Fan Li(李凡), Ruiqi Pan(潘瑞琪), Runyang Mo(莫润阳)^†, and Chenghui Wang(王成会)

Shaanxi Key Laboratory of Ultrasonics, Shaanxi Normal University, Xi'an 710119, China

Received:2022-11-16 Revised:2023-02-19 Accepted:2023-03-07 Online:2023-05-17 Published:2023-06-07
Contact: Runyang Mo E-mail:mmrryycn@snnu.edu.cn
Supported by:
Project supported by the National Natural Science Foundation of China (Grant Nos. 12074238, 11974232, and 11774212).

摘要/Abstract

摘要： Magnetic microbubbles (MMBs) have great potential applications in drug delivery and target therapy because they can be controlled by magnetic fields. In this paper, dynamic equations are derived by Lagrangian formalism and the behavior of MMBs subject to a combination field of magnetic and ultrasound field in an incompressible infinite fluid is analyzed numerically. The results show that the magnetic field can promote bubble expansion and hinder its translational motion, and both the enhancement and obstruction effects will weaken with the decrease of bubble size. The initial translational velocity has almost no effect on bubbles motion. Besides, the maximum expansion radius of MMBs increases with the ferrofluid shell thickness, while that of the common MBs is just the opposite. In addition, the periodic change of Levich viscous drag caused by the rebound leads to the step-like translational motion. Finally, the ferrofluid-shell model can be replaced by the model of non-magnetic microbubbles in magnetic liquid at high driving frequency.

关键词: magnetic microbubbles, ultrasound, magnetic field, translational motion

Abstract: Magnetic microbubbles (MMBs) have great potential applications in drug delivery and target therapy because they can be controlled by magnetic fields. In this paper, dynamic equations are derived by Lagrangian formalism and the behavior of MMBs subject to a combination field of magnetic and ultrasound field in an incompressible infinite fluid is analyzed numerically. The results show that the magnetic field can promote bubble expansion and hinder its translational motion, and both the enhancement and obstruction effects will weaken with the decrease of bubble size. The initial translational velocity has almost no effect on bubbles motion. Besides, the maximum expansion radius of MMBs increases with the ferrofluid shell thickness, while that of the common MBs is just the opposite. In addition, the periodic change of Levich viscous drag caused by the rebound leads to the step-like translational motion. Finally, the ferrofluid-shell model can be replaced by the model of non-magnetic microbubbles in magnetic liquid at high driving frequency.

Key words: magnetic microbubbles, ultrasound, magnetic field, translational motion

中图分类号: (Nonlinear acoustics)

43.25.+y

43.35.+d (Ultrasonics, quantum acoustics, and physical effects of sound) 47.55.dd (Bubble dynamics)

Zhiwei Du(杜芷玮), Fan Li(李凡), Ruiqi Pan(潘瑞琪), Runyang Mo(莫润阳), and Chenghui Wang(王成会). Effect of magnetic field on expansion of ferrofluid-encapsulated microbubble[J]. 中国物理B, 2023, 32(6): 64302-064302.

Zhiwei Du(杜芷玮), Fan Li(李凡), Ruiqi Pan(潘瑞琪), Runyang Mo(莫润阳), and Chenghui Wang(王成会). Effect of magnetic field on expansion of ferrofluid-encapsulated microbubble[J]. Chin. Phys. B, 2023, 32(6): 64302-064302.

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Effect of magnetic field on expansion of ferrofluid-encapsulated microbubble

Effect of magnetic field on expansion of ferrofluid-encapsulated microbubble

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