中国物理B ›› 2008, Vol. 17 ›› Issue (9): 3372-3377.doi: 10.1088/1674-1056/17/9/038

• CLASSICAL AREAS OF PHENOMENOLOGY • 上一篇    下一篇

Effects of vapour bubbles on acoustic and temperature distributions of therapeutic ultrasound

范庭波, 章东, 张喆, 马勇, 龚秀芬   

  1. Institute of Acoustics, Key Laboratory of Modern Acoustics, Nanjing University, Nanjing 210093, China
  • 收稿日期:2007-12-25 修回日期:2008-02-14 出版日期:2008-09-08 发布日期:2008-09-08
  • 基金资助:
    Project supported by Program for New Century Excellent Talents in University of China (06-0450) and National Natural Science Foundation of China (Grant No 10474044).

Effects of vapour bubbles on acoustic and temperature distributions of therapeutic ultrasound

Fan Ting-Bo(范庭波), Zhang Dong(章东)†, Zhang Zhe(张喆), Ma Yong(马勇), and Gong Xiu-Fen(龚秀芬)   

  1. Institute of Acoustics, Key Laboratory of Modern Acoustics, Nanjing University, Nanjing 210093, China
  • Received:2007-12-25 Revised:2008-02-14 Online:2008-09-08 Published:2008-09-08
  • Supported by:
    Project supported by Program for New Century Excellent Talents in University of China (06-0450) and National Natural Science Foundation of China (Grant No 10474044).

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摘要： This paper describes the evolution of vapour bubbles and its effect on nonlinear ultrasound propagation and temperature rise through tissues for therapeutic ultrasound. An acoustic-thermo coupling algorithm incorporating nonlinearity, diffraction, and temperature-dependent tissue properties, is employed to describe nonlinear ultrasound propagation and thermal effect. Results demonstrate that an obvious migration of peak pressure toward transducer surface is observed while the position of peak temperature changes little in liver tissue before the generation of vapour bubbles, and that the boiling region enlarges towards the surface of transducer in axial direction but increases slowly in radial direction after the generation of vapour bubbles.

Abstract: This paper describes the evolution of vapour bubbles and its effect on nonlinear ultrasound propagation and temperature rise through tissues for therapeutic ultrasound. An acoustic-thermo coupling algorithm incorporating nonlinearity, diffraction, and temperature-dependent tissue properties, is employed to describe nonlinear ultrasound propagation and thermal effect. Results demonstrate that an obvious migration of peak pressure toward transducer surface is observed while the position of peak temperature changes little in liver tissue before the generation of vapour bubbles, and that the boiling region enlarges towards the surface of transducer in axial direction but increases slowly in radial direction after the generation of vapour bubbles.

Key words: vapour bubbles, ultrasound propagation, temperature rise

中图分类号:  (Therapeutic applications)

  • 87.50.yt
43.25.Cb (Macrosonic propagation, finite amplitude sound; shock waves) 43.35.Ud (Thermoacoustics, high temperature acoustics, photoacoustic effect) 43.80.Jz (Use of acoustic energy (with or without other forms) in studies of structure and function of biological systems) 87.19.Pp (Biothermics and thermal processes in biology) 87.50.wp (Therapeutic applications)