Two-dimensional model of elastically coupled molecular motors

doi:10.1088/1674-1056/21/3/038701

中国物理B ›› 2012, Vol. 21 ›› Issue (3): 38701-038701.doi: 10.1088/1674-1056/21/3/038701

张红卫¹ ²,文书堂¹ ³,陈改荣³,李玉晓¹,曹中兴³,李伟³

收稿日期:2011-06-04 修回日期:2011-09-15 出版日期:2012-02-15 发布日期:2012-02-15
通讯作者: 文书堂,wensttnn@163.com E-mail:wensttnn@163.com

Two-dimensional model of elastically coupled molecular motors

Zhang Hong-Wei(张红卫)^a)b), Wen Shu-Tang(文书堂)^a)c)†, Chen Gai-Rong(陈改荣)^c), Li Yu-Xiao(李玉晓)^a), Cao Zhong-Xing(曹中兴)^c), and Li Wei(李伟)^c)

a. School of Physics and Engineering, Zhengzhou University, Zhengzhou 450052, China;
b. Department of Physics, Zhengzhou Normal University, Zhengzhou 450044, China;
c. School of Chemistry and Chemical Engineering, Xinxiang University, Xinxiang 453003, China

Received:2011-06-04 Revised:2011-09-15 Online:2012-02-15 Published:2012-02-15
Contact: Wen Shu-Tang,wensttnn@163.com E-mail:wensttnn@163.com
Supported by:
Project supported by the Educational Commission of Henan Province, China (Grant No. 2006140015) and the Science and Technology Planning Project of Henan Province, China (Grant No. 092300410142).

摘要/Abstract

Abstract: A flashing ratchet model of a two-headed molecular motor in a two-dimensional potential is proposed to simulate the hand-over-hand motion of kinesins. Extensive Langevin simulations of the model are performed. We discuss the dependences of motion and efficiency on the model parameters, including the external force and the temperature. A good qualitative agreement with the expected behavior is observed.

Key words: Brownian motors, ratchet, current, efficiency

中图分类号: (Structure of biomolecules)

87.15.B-

87.15.H- (Dynamics of biomolecules) 87.15.R- (Reactions and kinetics) 87.15.La (Mechanical properties)

张红卫, 文书堂, 陈改荣, 李玉晓, 曹中兴, 李伟. [J]. 中国物理B, 2012, 21(3): 38701-038701.

Zhang Hong-Wei(张红卫), Wen Shu-Tang(文书堂), Chen Gai-Rong(陈改荣), Li Yu-Xiao(李玉晓), Cao Zhong-Xing(曹中兴), and Li Wei(李伟) . Two-dimensional model of elastically coupled molecular motors[J]. Chin. Phys. B, 2012, 21(3): 38701-038701.

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Two-dimensional model of elastically coupled molecular motors

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