Electron beam irradiation on novel coronavirus (COVID-19): A Monte-Carlo simulation

doi:10.1088/1674-1056/ab7dac

中国物理B ›› 2020, Vol. 29 ›› Issue (4): 48703-048703.doi: 10.1088/1674-1056/ab7dac

• INTERDISCIPLINARY PHYSICS AND RELATED AREAS OF SCIENCE AND TECHNOLOGY • 上一篇下一篇

Electron beam irradiation on novel coronavirus (COVID-19): A Monte-Carlo simulation

Guobao Feng(封国宝), Lu Liu(刘璐), Wanzhao Cui(崔万照), Fang Wang(王芳)

1 National Key Laboratory of Science and Technology on Space Microwave, China Academy of Space Technology, Xi'an 710000, China;
2 School of Computer Science and Engineering, Xi'an University of Technology, Xi'an 710048, China;
3 Key Laboratory for Physical Electronics and Devices of the Ministry of Education, Xi'an Jiaotong University, Xi'an 710049, China

收稿日期:2020-02-17 修回日期:2020-02-20 出版日期:2020-04-05 发布日期:2020-04-05
通讯作者: Wanzhao Cui E-mail:cuiwanzhao@126.com
基金资助:
Project supported by the National Natural Science Foundation of China (Grant No. 61901360).

Electron beam irradiation on novel coronavirus (COVID-19): A Monte-Carlo simulation

Guobao Feng(封国宝)¹, Lu Liu(刘璐)², Wanzhao Cui(崔万照)¹, Fang Wang(王芳)³

1 National Key Laboratory of Science and Technology on Space Microwave, China Academy of Space Technology, Xi'an 710000, China;
2 School of Computer Science and Engineering, Xi'an University of Technology, Xi'an 710048, China;
3 Key Laboratory for Physical Electronics and Devices of the Ministry of Education, Xi'an Jiaotong University, Xi'an 710049, China

Received:2020-02-17 Revised:2020-02-20 Online:2020-04-05 Published:2020-04-05
Contact: Wanzhao Cui E-mail:cuiwanzhao@126.com
Supported by:
Project supported by the National Natural Science Foundation of China (Grant No. 61901360).

摘要/Abstract

摘要： The novel coronavirus pneumonia triggered by COVID-19 is now raging the whole world. As a rapid and reliable killing COVID-19 method in industry, electron beam irradiation can interact with virus molecules and destroy their activity. With the unexpected appearance and quickly spreading of the virus, it is urgently necessary to figure out the mechanism of electron beam irradiation on COVID-19. In this study, we establish a virus structure and molecule model based on the detected gene sequence of Wuhan patient, and calculate irradiated electron interaction with virus atoms via a Monte Carlo simulation that track each elastic and inelastic collision of all electrons. The characteristics of irradiation damage on COVID-19, atoms' ionizations and electron energy losses are calculated and analyzed with regions. We simulate the different situations of incident electron energy for evaluating the influence of incident energy on virus damage. It is found that under the major protecting of an envelope protein layer, the inner RNA suffers the minimal damage. The damage for a ～100-nm-diameter virus molecule is not always enhanced by irradiation energy monotonicity, for COVID-19, the irradiation electron energy of the strongest energy loss damage is 2 keV.

关键词: electron beam irradiation, novel coronavirus (COVID-19), numerical simulation

Abstract: The novel coronavirus pneumonia triggered by COVID-19 is now raging the whole world. As a rapid and reliable killing COVID-19 method in industry, electron beam irradiation can interact with virus molecules and destroy their activity. With the unexpected appearance and quickly spreading of the virus, it is urgently necessary to figure out the mechanism of electron beam irradiation on COVID-19. In this study, we establish a virus structure and molecule model based on the detected gene sequence of Wuhan patient, and calculate irradiated electron interaction with virus atoms via a Monte Carlo simulation that track each elastic and inelastic collision of all electrons. The characteristics of irradiation damage on COVID-19, atoms' ionizations and electron energy losses are calculated and analyzed with regions. We simulate the different situations of incident electron energy for evaluating the influence of incident energy on virus damage. It is found that under the major protecting of an envelope protein layer, the inner RNA suffers the minimal damage. The damage for a ～100-nm-diameter virus molecule is not always enhanced by irradiation energy monotonicity, for COVID-19, the irradiation electron energy of the strongest energy loss damage is 2 keV.

Key words: electron beam irradiation, novel coronavirus (COVID-19), numerical simulation

中图分类号: (Biomolecules: structure and physical properties)

87.15.-v

61.80.Fe (Electron and positron radiation effects) 52.65.Pp (Monte Carlo methods)

封国宝, 刘璐, 崔万照, 王芳. Electron beam irradiation on novel coronavirus (COVID-19): A Monte-Carlo simulation[J]. 中国物理B, 2020, 29(4): 48703-048703.

Guobao Feng(封国宝), Lu Liu(刘璐), Wanzhao Cui(崔万照), Fang Wang(王芳). Electron beam irradiation on novel coronavirus (COVID-19): A Monte-Carlo simulation[J]. Chin. Phys. B, 2020, 29(4): 48703-048703.

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Electron beam irradiation on novel coronavirus (COVID-19): A Monte-Carlo simulation

Electron beam irradiation on novel coronavirus (COVID-19): A Monte-Carlo simulation

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