Simulation study of a magnetocardiogram based on a virtual heart model: effect of a cardiac equivalent source and a volume conductor

doi:10.1088/1674-1056/20/3/030702

中国物理B ›› 2011, Vol. 20 ›› Issue (3): 30702-030702.doi: 10.1088/1674-1056/20/3/030702

Simulation study of a magnetocardiogram based on a virtual heart model: effect of a cardiac equivalent source and a volume conductor

寿国法¹, 夏灵¹, 戴灵¹, 唐发宽², 马平³

(1)Department of Biomedical Engineering, Key Laboratory for Biomedical Engineering of the Ministry of Education, Zhejiang University, Hangzhou 310027, China; (2)Department of Cardiology, the 309th Hospital of the People's Liberation Army, Beijing 100091, China; (3)Department of Physics, State Key Laboratory for Artificial Microstructure and Mesoscopic Physics, Peking University, Beijing 100871, China

收稿日期:2010-08-05 修回日期:2010-09-08 出版日期:2011-03-15 发布日期:2011-03-15
基金资助:
Project supported by the State Key Development Program for Basic Research of China (Grant Nos. 2007CB512100 and 2006CB601007), the National Natural Science Foundation of China (Grant No. 10674006), the National High Technology Research and Development Pro

Simulation study of a magnetocardiogram based on a virtual heart model: effect of a cardiac equivalent source and a volume conductor

Shou Guo-Fa(寿国法)^a), Xia Ling(夏灵)^a)†, Ma Ping(马平)^b), Tang Fa-Kuan(唐发宽)^c)‡, and Dai Ling(戴灵)^a)

^a Department of Biomedical Engineering, Key Laboratory for Biomedical Engineering of the Ministry of Education, Zhejiang University, Hangzhou 310027, China; ^b Department of Physics, State Key Laboratory for Artificial Microstructure and Mesoscopic Physics, Peking University, Beijing 100871, China; ^c Department of Cardiology, the 309th Hospital of the People's Liberation Army, Beijing 100091, China

Received:2010-08-05 Revised:2010-09-08 Online:2011-03-15 Published:2011-03-15
Supported by:
Project supported by the State Key Development Program for Basic Research of China (Grant Nos. 2007CB512100 and 2006CB601007), the National Natural Science Foundation of China (Grant No. 10674006), the National High Technology Research and Development Program of China (Grant No. 2007AA03Z238), China Postdoctoral Science Foundation (Grant No. 20090461376), and the Fundamental Research Funds for the Central Universities (Grant No. KYJD09001).

摘要/Abstract

摘要： In this paper, we present a magnetocardiogram (MCG) simulation study using the boundary element method (BEM) and based on the virtual heart model and the realistic human volume conductor model. The different contributions of cardiac equivalent source models and volume conductor models to the MCG are deeply and comprehensively investigated. The single dipole source model, the multiple dipoles source model and the equivalent double layer (EDL) source model are analysed and compared with the cardiac equivalent source models. Meanwhile, the effect of the volume conductor model on the MCG combined with these cardiac equivalent sources is investigated. The simulation results demonstrate that the cardiac electrophysiological information will be partly missed when only the single dipole source is taken, while the EDL source is a good option for MCG simulation and the effect of the volume conductor is smallest for the EDL source. Therefore, the EDL source is suitable for the study of MCG forward and inverse problems, and more attention should be paid to it in future MCG studies.

关键词: virtual heart model, magnetocardiogram, dipole source, equivalent double layer source, volume conductor model

Abstract: In this paper, we present a magnetocardiogram (MCG) simulation study using the boundary element method (BEM) and based on the virtual heart model and the realistic human volume conductor model. The different contributions of cardiac equivalent source models and volume conductor models to the MCG are deeply and comprehensively investigated. The single dipole source model, the multiple dipoles source model and the equivalent double layer (EDL) source model are analysed and compared with the cardiac equivalent source models. Meanwhile, the effect of the volume conductor model on the MCG combined with these cardiac equivalent sources is investigated. The simulation results demonstrate that the cardiac electrophysiological information will be partly missed when only the single dipole source is taken, while the EDL source is a good option for MCG simulation and the effect of the volume conductor is smallest for the EDL source. Therefore, the EDL source is suitable for the study of MCG forward and inverse problems, and more attention should be paid to it in future MCG studies.

Key words: virtual heart model, magnetocardiogram, dipole source, equivalent double layer source, volume conductor model

中图分类号: (Computer modeling and simulation)

07.05.Tp

寿国法, 夏灵, 马平, 唐发宽, 戴灵. Simulation study of a magnetocardiogram based on a virtual heart model: effect of a cardiac equivalent source and a volume conductor[J]. 中国物理B, 2011, 20(3): 30702-030702.

Shou Guo-Fa(寿国法), Xia Ling(夏灵), Ma Ping(马平), Tang Fa-Kuan(唐发宽), and Dai Ling(戴灵). Simulation study of a magnetocardiogram based on a virtual heart model: effect of a cardiac equivalent source and a volume conductor[J]. Chin. Phys. B, 2011, 20(3): 30702-030702.

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Simulation study of a magnetocardiogram based on a virtual heart model: effect of a cardiac equivalent source and a volume conductor

Simulation study of a magnetocardiogram based on a virtual heart model: effect of a cardiac equivalent source and a volume conductor

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