中国物理B ›› 2011, Vol. 20 ›› Issue (3): 30503-030503.doi: 10.1088/1674-1056/20/3/030503

• • 上一篇    下一篇

Effects of an electromagnetic field on intracellular calcium oscillations in a cell with external noise

杨林静1, 段卫龙2, 梅冬成2   

  1. (1)College of Chinese Medicine, Yunnan University of Traditional Chinese Medicine, Kunming 650031, China; (2)Department of Physics, Yunnan University, Kunming 650091, China
  • 收稿日期:2010-09-06 修回日期:2010-09-28 出版日期:2011-03-15 发布日期:2011-03-15
  • 基金资助:
    Project supported by the National Natural Science Foundation of China (Grant No. 10865006) and the Science Foundation of Yunnan University, China (Grant No. 2009A001Z).

Effects of an electromagnetic field on intracellular calcium oscillations in a cell with external noise

Duan Wei-Long(段卫龙)a),Yang Lin-Jing(杨林静)b),and Mei Dong-Cheng(梅冬成)a)   

  1. a Department of Physics, Yunnan University, Kunming 650091, China; b College of Chinese Medicine, Yunnan University of Traditional Chinese Medicine, Kunming 650031, China
  • Received:2010-09-06 Revised:2010-09-28 Online:2011-03-15 Published:2011-03-15
  • Supported by:
    Project supported by the National Natural Science Foundation of China (Grant No. 10865006) and the Science Foundation of Yunnan University, China (Grant No. 2009A001Z).

摘要: Intracellular calcium ion concentration oscillation in a cell subjected to external noise and irradiated by an electromagnetic field is considered. The effects of the intensity E0, the polar angle θ and the frequency omega of the external electric field on steady-state probability distribution and the mean Ca2+ concentration, respectively, are investigated by a numerical calculation method. The results indicate that (i) variation of ω cannot affect the intracellular calcium oscillation; (ii) the steady-state probability distribution presents a meaningful modification due to the variations of E0 and θ, while variation of θ does not affect the steady-state probability distribution under the condition of a small E0, and E0 cannot affect the steady-state probability distribution either when θ = π/2; (iii) the mean Ca2+ concentration increases as E0 increases when θ < π/2 and, as θ increases, it first increases and then decreases. However, it does not vary with E0 increasing when θ = π/2, but it increases with θ increasing when E0 is small.

关键词: fluctuation phenomena, interactions of biosystems with radiations

Abstract: Intracellular calcium ion concentration oscillation in a cell subjected to external noise and irradiated by an electromagnetic field is considered. The effects of the intensity $E_{0}$, the polar angle $\theta $ and  the frequency $\omega $ of the external electric field on steady-state probability distribution and the mean Ca$^{2 + }$ concentration, respectively, are investigated by a numerical calculation method. The results indicate  that (i) variation of $\omega $ cannot affect the intracellular calcium oscillation; (ii) the steady-state probability distribution presents a meaningful modification due to the variations of $E_{0} $ and $\theta $, while variation of $\theta $ does not affect the steady-state probability distribution under the condition of a small $E_0 $, and $E_0 $ cannot affect the steady-state probability distribution either when $\theta = \pi/2$; (iii) the  mean Ca$^{2 + }$ concentration increases as $E_0 $ increases when $\theta < \pi / 2$ and, as $\theta $ increases, it first increases and then decreases. However, it does not vary with $E_0 $ increasing when $\theta = \pi/2$,  but it increases with $\theta $ increasing when $E_0 $ is small.

Key words: fluctuation phenomena, interactions of biosystems with radiations

中图分类号:  (Fluctuation phenomena, random processes, noise, and Brownian motion)

  • 05.40.-a
87.50.-a (Effects of electromagnetic and acoustic fields on biological systems)