中国物理B ›› 2009, Vol. 18 ›› Issue (7): 3066-3072.doi: 10.1088/1674-1056/18/7/076

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An effective scatter correction method based on single scatter simulation for a 3D whole-body PET scanner

Yamada Ryoko1, Watanabe Mitsuo1, 高飞2, 刘华锋2   

  1. (1)Central Research Laboratory, Hamamatsu Photonics K.K., Hamamatsu 434-8601, Japan; (2)State Key Laboratory of Modern Optical Instrumentation, Zhejiang University, Hangzhou 310027, China
  • 收稿日期:2008-11-24 修回日期:2009-01-12 出版日期:2009-07-20 发布日期:2009-07-20
  • 基金资助:
    Project supported by the National Natural Science Foundation of China (Grant No 60772125), the Key Foundation of Guangdong Province of China (Grant No 07117784), and Scientific Plan of Zhejiang Province of China (Grant No 2008C23060).

An effective scatter correction method based on single scatter simulation for a 3D whole-body PET scanner

Gao Fei(高飞)a), Yamada Ryokob), Watanabe Mitsuob), and Liu Hua-Feng(刘华锋)a)   

  1. a State Key Laboratory of Modern Optical Instrumentation, Zhejiang University, Hangzhou 310027, China; b Central Research Laboratory, Hamamatsu Photonics K.K., Hamamatsu 434-8601, Japan
  • Received:2008-11-24 Revised:2009-01-12 Online:2009-07-20 Published:2009-07-20
  • Supported by:
    Project supported by the National Natural Science Foundation of China (Grant No 60772125), the Key Foundation of Guangdong Province of China (Grant No 07117784), and Scientific Plan of Zhejiang Province of China (Grant No 2008C23060).

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摘要： Hamamatsu SHR74000 is a newly designed full three-dimensional (3D) whole body positron emission tomography (PET) scanner with small crystal size and large field of view (FOV). With the improvement of sensitivity, the scatter events increase significantly at the same time, especially for large objects. Monte Carlo simulations help us to understand the scatter phenomena and provide good references for scatter correction. In this paper, we introduce an effective scatter correction method based on single scatter simulation for the new PET scanner, which accounts for the full 3D scatter correction. With the results from Monte Carlo simulations, we implement a new scale method with special concentration on scatter events from outside the axial FOV and multiple scatter events. The effects of scatter correction are investigated and evaluated by phantom experiments; the results show good improvements in quantitative accuracy and contrast of the images, even for large objects.

Abstract: Hamamatsu SHR74000 is a newly designed full three-dimensional (3D) whole body positron emission tomography (PET) scanner with small crystal size and large field of view (FOV). With the improvement of sensitivity, the scatter events increase significantly at the same time, especially for large objects. Monte Carlo simulations help us to understand the scatter phenomena and provide good references for scatter correction. In this paper, we introduce an effective scatter correction method based on single scatter simulation for the new PET scanner, which accounts for the full 3D scatter correction. With the results from Monte Carlo simulations, we implement a new scale method with special concentration on scatter events from outside the axial FOV and multiple scatter events. The effects of scatter correction are investigated and evaluated by phantom experiments; the results show good improvements in quantitative accuracy and contrast of the images, even for large objects.

Key words: positron emission tomography, scatter correction, single scatter simulation, Monte Carlo

中图分类号:  (Positron emission tomography (PET))

  • 87.57.uk
87.56.Da (Ancillary equipment) 02.70.Uu (Applications of Monte Carlo methods)