Measurement of T wave in magnetocardiography using tunnel magnetoresistance sensor

doi:10.1088/1674-1056/aca5fe

中国物理B ›› 2023, Vol. 32 ›› Issue (2): 20703-020703.doi: 10.1088/1674-1056/aca5fe

Measurement of T wave in magnetocardiography using tunnel magnetoresistance sensor

Zhihong Lu(陆知宏)^1,2,3, Shuai Ji(纪帅)^1,2,3, and Jianzhong Yang(杨建中)^1,2,3,†

1 Department of Precision Instrument, Tsinghua University, Beijing 100084, China;
2 Beijing Innovation Center for Future Chips, Beijing 100084, China;
3 State Key Laboratory of Precision Measurement Technology and Instruments, Tsinghua University, Beijing 100084, China

收稿日期:2022-06-01 修回日期:2022-10-22 接受日期:2022-11-25 出版日期:2023-01-10 发布日期:2023-01-10
通讯作者: Jianzhong Yang E-mail:yang-jz@tsinghua.edu.cn
基金资助:
Project supported by the Suzhou Tsinghua innovation leading action project (Grant No. 2016SZ0217) and the National Key Research and Development Program of China (Grant No. 2016YFB0500902).

Measurement of T wave in magnetocardiography using tunnel magnetoresistance sensor

Zhihong Lu(陆知宏)^1,2,3, Shuai Ji(纪帅)^1,2,3, and Jianzhong Yang(杨建中)^1,2,3,†

1 Department of Precision Instrument, Tsinghua University, Beijing 100084, China;
2 Beijing Innovation Center for Future Chips, Beijing 100084, China;
3 State Key Laboratory of Precision Measurement Technology and Instruments, Tsinghua University, Beijing 100084, China

Received:2022-06-01 Revised:2022-10-22 Accepted:2022-11-25 Online:2023-01-10 Published:2023-01-10
Contact: Jianzhong Yang E-mail:yang-jz@tsinghua.edu.cn
Supported by:
Project supported by the Suzhou Tsinghua innovation leading action project (Grant No. 2016SZ0217) and the National Key Research and Development Program of China (Grant No. 2016YFB0500902).

摘要/Abstract

摘要： Several critical clinical applications of magnetocardiography (MCG) involve its T wave. The T wave's accuracy directly affects the diagnostic accuracy of MCG for ischemic heart disease and arrhythmogenic. Tunnel magnetoresistance (TMR) attracts attention as a new MCG measurement technique. However, the T waves measured by TMR are often drowned in noise. The accuracy of T waves needs to be discussed to determine the clinical value of MCG measured by TMR. This study uses an improved empirical mode decomposition (EMD) algorithm and averaging to eliminate the noise in the MCG measured by TMR. The MCG signals measured by TMR are compared with MCG measured by the optically pumped magnetometer (OPM) to judge its accuracy. Using the MCG measured by OPM as a reference, the relative errors in time and amplitude of the T wave measured by TMR are 3.4% and 1.8%, respectively. This is the first demonstration that TMR can accurately measure the time and amplitude of MCG T waves. The ability to provide reliable T wave data illustrates the significant clinical application value of TMR in MCG measurement.

关键词: magnetocardiography, tunnel magnetoresistance, optically pumped magnetometer, T wave detection

Abstract: Several critical clinical applications of magnetocardiography (MCG) involve its T wave. The T wave's accuracy directly affects the diagnostic accuracy of MCG for ischemic heart disease and arrhythmogenic. Tunnel magnetoresistance (TMR) attracts attention as a new MCG measurement technique. However, the T waves measured by TMR are often drowned in noise. The accuracy of T waves needs to be discussed to determine the clinical value of MCG measured by TMR. This study uses an improved empirical mode decomposition (EMD) algorithm and averaging to eliminate the noise in the MCG measured by TMR. The MCG signals measured by TMR are compared with MCG measured by the optically pumped magnetometer (OPM) to judge its accuracy. Using the MCG measured by OPM as a reference, the relative errors in time and amplitude of the T wave measured by TMR are 3.4% and 1.8%, respectively. This is the first demonstration that TMR can accurately measure the time and amplitude of MCG T waves. The ability to provide reliable T wave data illustrates the significant clinical application value of TMR in MCG measurement.

Key words: magnetocardiography, tunnel magnetoresistance, optically pumped magnetometer, T wave detection

中图分类号: (Sensors (chemical, optical, electrical, movement, gas, etc.); remote sensing)

07.07.Df

07.55.Ge (Magnetometers for magnetic field measurements)

Zhihong Lu(陆知宏), Shuai Ji(纪帅), and Jianzhong Yang(杨建中). Measurement of T wave in magnetocardiography using tunnel magnetoresistance sensor[J]. 中国物理B, 2023, 32(2): 20703-020703.

Zhihong Lu(陆知宏), Shuai Ji(纪帅), and Jianzhong Yang(杨建中). Measurement of T wave in magnetocardiography using tunnel magnetoresistance sensor[J]. Chin. Phys. B, 2023, 32(2): 20703-020703.

参考文献

[1] Mäkijärvi M, Korhonen P, Jurkko R, Väänänen H, Siltanen P, and Hänninen H 2010 Comprehensive Electrocardiology (London: Springer) pp. 2007-2028
[2] Nalbach M and Dössel O 2002 Physica C 372-376 254258
[3] Fenici R, Brisinda D and Meloni A M 2005 Expert Rev. Mol. Diagn. 5 291
[4] Jensen K, Skarsfeldt M A, Stærkind H, Arnbak J, Balabas M V, Olesen S, Bentzen B H and Polzik E S 2018 Sci. Rep. 8 16218
[5] Kim Y J, Savukov I and Newman S 2019 Appl. Phys. Lett. 114 143702
[6] Lembke G, Erné S N, Nowak H, Menhorn B and Pasquarelli A 2014 Biomed. Opt. Express 5 876
[7] Zhao W L, Tao X C, Ye C F and Tao Y 2022 Sensors 22 1021
[8] Fujiwara K, Oogane M, Kanno A, Imada M, Jono J, Terauchi T, Okuno T, Aritomi Y, Morikawa M, Tsuchida M, Nakasato N and Ando Y 2018 Appl. Phys. Express 11 023001
[9] Wang M L, Wang Y, Peng L and Ye C F 2019 IEEE Sens. J. 19 1
[10] Oogane M, Fujiwara K, Kanno A, Nakano T, Wagatsuma H, Arimoto T, Mizukami S, Kumagai S, Matsuzaki H, Nakasato N and Ando Y 2021 Appl. Phys. Express 12 123002
[11] Mariyappa N, Parasakthi C, Sengottuvel S, Gireesan K, Patel R, Janawadkar M P, Sundar C S and Radhakrishnan T S 2012 Physica C 477 15
[12] Zhu K and Kiourti A 2022 IEEE Open J. Antennas Propag. 3 732
[13] Vink A S, Neumann B, Lieve K V, Sinner M F, Hofman N, Kadi E S, Schoenmaker M HA, Slaghekke H M J, de Jong J S S G, Clur S B, Blom N A, Kääb S, Wilde A A M and Postema P G 2018 Circulation 138 2345
[14] Watanabe S and Yamada S 2008 J. Arrhythmia 24 417
[15] Horigome H, Takahashi M I, Asaka M, Shigemitsu S, Kandori A and Tsukada K 2000 Acta Paediatr. 89 64
[16] Tang P T, Shenasa M and Boyle N G 2017 Card. Electrophysiol Clin. 9 693
[17] Zhang S L and Cao N 2020 Chin. Phys. B 29 040702
[18] Zhu K, Shah A M, Berkow J and Kiourti A 2021 IEEE J. Electromagn. RF Microw. Med. Biol. 5 124
[19] Zhang Y, Wolters N, Schubert J, Lomparski D, Banzet M, Panaitov G, Krause H J, Muck M and Braginski A I 2003 IEEE Trans. Appl. Supercond. 13 389
[20] Li J J, Du P C, Fu J Q, Fu J Q, Wang X T, Zhou Q and Wang R Q 2019 Chin. Phys. B 28 040703
[21] Huang N E, Shen Z, Long S, Wu M L, Shih H, Zheng Q, Yen N C, Tung C C and Liu H 1998 Proc. Math. Phys. Eng. Sci. 454 903
[22] Wu Z H and Huang N E 2009 Adv. Adapt. Data Analysis 1 141
[23] Torres M E, Colominas M, Schlotthauer G and Flandrin P 2011 IEEE International Conference on Acoustics, Speech and Signal Processing, May 22-27, 2011, Prague, Czech Republic, p. 4144
[24] Colominas M A, Schlotthauer G and Torres M E 2014 Biomed Signal Process Control 14 19
[25] Liao Y P, He C C and Guo Q 2018 Symmetry 10 269
[26] Patrick E M, Gari D C, Lionel T and Leonard A S 2003 IEEE. Trans. Biomed. Eng. 50 289

Measurement of T wave in magnetocardiography using tunnel magnetoresistance sensor

Measurement of T wave in magnetocardiography using tunnel magnetoresistance sensor

RichHTML

PDF (PC)

赞

可视化

摘要/Abstract

引用本文

使用本文

参考文献

相关文章 15

Metrics

本文评价

推荐阅读 0

[1]	Kang Yang(杨康), Hong-Wei Zhang(张宏伟), Qian-Nian Zhang(张千年),Jun-Jun Zha(查君君), and Deng-Chao Huang(黄登朝). Residual field suppression for magnetocardiography measurement inside a thin magnetically shielded room using bi-planar coil[J]. 中国物理B, 2022, 31(7): 70701-070701.
[2]	Peng-Bin Niu(牛鹏斌), Bo-Xiang Cui(崔博翔), and Hong-Gang Luo(罗洪刚). Negative tunnel magnetoresistance in a quantum dot induced by interplay of a Majorana fermion and thermal-driven ferromagnetic leads[J]. 中国物理B, 2021, 30(9): 97401-097401.
[3]	张树林, 曹宁. A synthetic optically pumped gradiometer for magnetocardiography measurements[J]. 中国物理B, 2020, 29(4): 40702-040702.
[4]	郁扬, 胡雯婕, 李强, 时倩, 朱银燕, 林汉轩, 苗田, 白羽, 王艳梅, 杨文婷, 王文彬, 郭杭闻, 殷立峰, 沈健. Visualization of tunnel magnetoresistance effect in single manganite nanowires[J]. 中国物理B, 2020, 29(1): 18501-018501.
[5]	杜鹏程, 李建军, 杨思嘉, 王旭桐, 卓彦, 王帆, 王如泉. Observing the steady-state visual evoked potentials with a compact quad-channel spin exchange relaxation-free magnetometer[J]. 中国物理B, 2019, 28(4): 40702-040702.
[6]	李茹杰, 全伟, 范文峰, 邢力, 王卓, 翟跃阳, 房建成. A dual-axis, high-sensitivity atomic magnetometer[J]. 中国物理B, 2017, 26(12): 120702-120702.
[7]	邱阳, 李华, 张树林, 王永良, 孔祥燕, 张朝祥, 张永升, 徐小峰, 杨康, 谢晓明. Low-T_c direct current superconducting quantum interference device magnetometer-based 36-channel magnetocardiography system in a magnetically shielded room[J]. 中国物理B, 2015, 24(7): 78501-078501.
[8]	李华, 张树林, 邱阳, 张永升, 张朝祥, 孔祥燕, 谢晓明. Baseline optimization of SQUID gradiometer for magnetocardiography[J]. 中国物理B, 2015, 24(2): 28501-028501.
[9]	邱阳, 刘超, 张树林, 张国峰, 王永良, 李华, 曾佳, 孔祥燕, 谢晓明. A SQUID gradiometer module with large junction shunt resistors[J]. , 2014, 23(8): 88503-088503.
[10]	朱俊杰, 蒋式勤, 王伟远, 赵晨, 吴燕华, 罗明, 权薇薇. Cardiac electrical activity imaging of patients with CRBBB or CLBBB in magnetocardiography[J]. 中国物理B, 2014, 23(4): 48702-048702.
[11]	张树林, 张国峰, 王永良, 刘明, 李华, 邱阳, 曾佳, 孔祥燕, 谢晓明. Multichannel fetal magnetocardiography using SQUID bootstrap circuit[J]. 中国物理B, 2013, 22(12): 128501-128501.
[12]	刘新元, 裴留庆, 王寅, 张素明, 高红蕾, 戴远东. Characteristic parameters of electromagnetic signals from a human heart system[J]. 中国物理B, 2011, 20(4): 47401-047401.
[13]	王倩, 马平, 陆宏, 唐雪正, 华宁, 唐发宽. Inverse computation for cardiac sources using single current dipole and current multipole models[J]. 中国物理B, 2009, 18(12): 5566-5574.
[14]	李倬, 刘当婷, 田野, 陈赓华, 张利华, 杨乾声, 冯稷. Singular value decomposition with normalized period for magnetocaridiography signal processing[J]. 中国物理B, 2007, 16(10): 2913-2917.
[15]	李倬, 陈庚华, 张利华, 杨乾声, 冯稷. An NLMS algorithm with optimized preparatory step-size parameters for SQUID-based MCG data processing[J]. 中国物理B, 2006, 15(2): 310-314.