中国物理B ›› 2020, Vol. 29 ›› Issue (4): 40702-040702.doi: 10.1088/1674-1056/ab7801

• SPECIAL TOPIC—Recent advances in thermoelectric materials and devices • 上一篇    下一篇

A synthetic optically pumped gradiometer for magnetocardiography measurements

Shu-Lin Zhang(张树林), Ning Cao(曹宁)   

  1. 1 Joint Laboratory of Bioimaging Technology and Applications, CAS-SIMIT&MEDI, Shanghai 201899, China;
    2 State Key Laboratory of Functional Materials for Informatics, Institute of Microsystem and Information Technology(SIMIT), Chinese Academy of Sciences(CAS), Shanghai 200050, China;
    3 Centre for Excellence in Superconducting Electronics, Chinese Academy of Sciences, Shanghai 200050, China;
    4 Shanghai Medi Instruments Ltd., Shanghai 201899, China
  • 收稿日期:2019-12-13 修回日期:2020-02-08 出版日期:2020-04-05 发布日期:2020-04-05
  • 通讯作者: Shu-Lin Zhang E-mail:zhangsl@mail.sim.ac.cn
  • 基金资助:
    Project supported by the National Natural Science Foundation of China (Grant No. 61701486).

A synthetic optically pumped gradiometer for magnetocardiography measurements

Shu-Lin Zhang(张树林)1,2,3, Ning Cao(曹宁)1,4   

  1. 1 Joint Laboratory of Bioimaging Technology and Applications, CAS-SIMIT&MEDI, Shanghai 201899, China;
    2 State Key Laboratory of Functional Materials for Informatics, Institute of Microsystem and Information Technology(SIMIT), Chinese Academy of Sciences(CAS), Shanghai 200050, China;
    3 Centre for Excellence in Superconducting Electronics, Chinese Academy of Sciences, Shanghai 200050, China;
    4 Shanghai Medi Instruments Ltd., Shanghai 201899, China
  • Received:2019-12-13 Revised:2020-02-08 Online:2020-04-05 Published:2020-04-05
  • Contact: Shu-Lin Zhang E-mail:zhangsl@mail.sim.ac.cn
  • Supported by:
    Project supported by the National Natural Science Foundation of China (Grant No. 61701486).

摘要: Magnetocardiography (MCG) measurement is important for investigating the cardiac biological activities. Traditionally, the extremely weak MCG signal was detected by using superconducting quantum interference devices (SQUIDs). As a room-temperature magnetic-field sensor, optically pumped magnetometer (OPM) has shown to have comparable sensitivity to that of SQUIDs, which is very suitable for biomagnetic measurements. In this paper, a synthetic gradiometer was constructed by using two OPMs under spin-exchange relaxation-free (SERF) conditions within a moderate magnetically shielded room (MSR). The magnetic noise of the OPM was measured to less than 70 fT/Hz1/2. Under a baseline of 100 mm, noise cancellation of about 30 dB was achieved. MCG was successfully measured with a signal to noise ratio (SNR) of about 37 dB. The synthetic gradiometer technique was very effective to suppress the residual environmental fields, demonstrating the OPM gradiometer technique for highly cost-effective biomagnetic measurements.

关键词: optically pumped magnetometer (OPM), magnetocardiography (MCG), gradiometer

Abstract: Magnetocardiography (MCG) measurement is important for investigating the cardiac biological activities. Traditionally, the extremely weak MCG signal was detected by using superconducting quantum interference devices (SQUIDs). As a room-temperature magnetic-field sensor, optically pumped magnetometer (OPM) has shown to have comparable sensitivity to that of SQUIDs, which is very suitable for biomagnetic measurements. In this paper, a synthetic gradiometer was constructed by using two OPMs under spin-exchange relaxation-free (SERF) conditions within a moderate magnetically shielded room (MSR). The magnetic noise of the OPM was measured to less than 70 fT/Hz1/2. Under a baseline of 100 mm, noise cancellation of about 30 dB was achieved. MCG was successfully measured with a signal to noise ratio (SNR) of about 37 dB. The synthetic gradiometer technique was very effective to suppress the residual environmental fields, demonstrating the OPM gradiometer technique for highly cost-effective biomagnetic measurements.

Key words: optically pumped magnetometer (OPM), magnetocardiography (MCG), gradiometer

中图分类号:  (Sensors (chemical, optical, electrical, movement, gas, etc.); remote sensing)

  • 07.07.Df
87.85.Ox (Biomedical instrumentation and micro-electro-mechanical systems (MEMS)) 07.55.Ge (Magnetometers for magnetic field measurements)