Effect of terahertz pulse on gene expression in human eye cells

doi:10.1088/1674-1056/28/4/048703

中国物理B ›› 2019, Vol. 28 ›› Issue (4): 48703-048703.doi: 10.1088/1674-1056/28/4/048703

• INTERDISCIPLINARY PHYSICS AND RELATED AREAS OF SCIENCE AND TECHNOLOGY • 上一篇下一篇

Effect of terahertz pulse on gene expression in human eye cells

1 School of Precision Instrument and Opto-electronics Engineering, The Center for Terahertz Waves, Tianjin University, Tianjin 300072, China;
2 Eye Institute and School of Optometry and Ophthalmology, Tianjin Medical University Eye Hospital, Tianjin 300384, China;
3 Key Laboratory of Opto-electronics Information Technology and Technical Science, Ministry of Education, Tianjin University, Tianjin 300072, China;
4 State Key Laboratory of Precision Measuring Technology and Instruments, Tianjin University, Tianjin 300072, China

收稿日期:2018-10-12 修回日期:2019-01-31 出版日期:2019-04-05 发布日期:2019-04-05
通讯作者: Ming-Xia He E-mail:hhmmxx@tju.edu.cn
基金资助:
Project supported by the National Natural Science Foundation of China (Grant Nos. 61675151 and 81570872), the Tianjin Municipal Science and Technology Commission Grants, China (Grant No. 15JCYBJC24900), and the Clinical Research Foundation of Tianjin Medical University Eye Institute, China (Grant No. 16YKJS002).

Effect of terahertz pulse on gene expression in human eye cells

Jin-Wu Zhao(赵晋武)^1,4, Ming-Xia He(何明霞)^1,4, Li-Jie Dong(东莉洁)², Shao-Xian Li(李绍限)^1,3, Li-Yuan Liu(刘立媛)^1,3, Shao-Chong Bu(步绍翀)², Chun-Mei Ouyang(欧阳春梅)^1,3, Peng-Fei Wang(王鹏騛)^1,4, Long-Ling Sun(孙珑玲)^1,4

1 School of Precision Instrument and Opto-electronics Engineering, The Center for Terahertz Waves, Tianjin University, Tianjin 300072, China;
2 Eye Institute and School of Optometry and Ophthalmology, Tianjin Medical University Eye Hospital, Tianjin 300384, China;
3 Key Laboratory of Opto-electronics Information Technology and Technical Science, Ministry of Education, Tianjin University, Tianjin 300072, China;
4 State Key Laboratory of Precision Measuring Technology and Instruments, Tianjin University, Tianjin 300072, China

Received:2018-10-12 Revised:2019-01-31 Online:2019-04-05 Published:2019-04-05
Contact: Ming-Xia He E-mail:hhmmxx@tju.edu.cn
Supported by:
Project supported by the National Natural Science Foundation of China (Grant Nos. 61675151 and 81570872), the Tianjin Municipal Science and Technology Commission Grants, China (Grant No. 15JCYBJC24900), and the Clinical Research Foundation of Tianjin Medical University Eye Institute, China (Grant No. 16YKJS002).

摘要/Abstract

摘要：

In recent years, the advances in terahertz applications have stimulated interest in the biological effects associated with this frequency range. We study the gene expression profile in three types of cells exposed to terahertz radiation, i.e., human ARPE-19 retinal pigment epithelial cells, simian virus 40-transformed human corneal epithelial cells, and human MIO-M1 Müller cells. We find that the gene expression in response to heat shock is unaffected, indicating that the minimum temperature increases under controlled environment. The transcriptome sequencing survey demonstrates that 6-hour irradiation with a broadband terahertz source results in specific change in gene expression and also the biological functions that are closely related to these genes. Our results imply that the effect of terahertz radiation on gene expression can last over 15 hours and depends on the type of cell.

关键词: terahertz radiation, eye cells, gene expression

Abstract:

Key words: terahertz radiation, eye cells, gene expression

中图分类号: (Effects of electromagnetic and acoustic fields on biological systems)

87.50.-a

87.10.Vg (Biological information) 42.62.Be (Biological and medical applications) 87.50.up (Dosimetry/exposure assessment)

赵晋武, 何明霞, 东莉洁, 李绍限, 刘立媛, 步绍翀, 欧阳春梅, 王鹏騛, 孙珑玲. Effect of terahertz pulse on gene expression in human eye cells[J]. 中国物理B, 2019, 28(4): 48703-048703.

Jin-Wu Zhao(赵晋武), Ming-Xia He(何明霞), Li-Jie Dong(东莉洁), Shao-Xian Li(李绍限), Li-Yuan Liu(刘立媛), Shao-Chong Bu(步绍翀), Chun-Mei Ouyang(欧阳春梅), Peng-Fei Wang(王鹏騛), Long-Ling Sun(孙珑玲). Effect of terahertz pulse on gene expression in human eye cells[J]. Chin. Phys. B, 2019, 28(4): 48703-048703.

参考文献 38

[1]	Ferguson B and Zhang X 2002 Nat. Mater. 1 26 doi: 10.1038/nmat708
[2]	Lewis R A 2014 J. Phys. D: Appl. Phys. 47 374001 doi: 10.1088/0022-3727/47/37/374001
[3]	Wilmink G J and Grundt J E 2011 J. Infrared Millim. Terahertz Waves 32 1074 doi: 10.1007/s10762-011-9794-5
[4]	Wang Y, Ren Y, Chen L, Song C, Li C, Zhang C, Xu D and Yao J 2018 Chin. Phys. B 27 114204 doi: 10.1088/1674-1056/27/11/114204
[5]	Liu C, Wang C, Cao J 2016 Chin. Phys. B 25 028702 doi: 10.1088/1674-1056/25/2/028702
[6]	Whitmire S E, Wolpert D, Markelz A G, Hillebrecht J R, Galan J and Birge R R 2003 Biophys. J. 85 1269 doi: 10.1016/S0006-3495(03)74562-7
[7]	Fischer B M, Walther M and Uhd Jepsen P 2002 Phys. Med. Biol. 47 3807 doi: 10.1088/0031-9155/47/21/319
[8]	Clothier R H and Bourne N 2003 J. Biol. Phys. 29 179 doi: 10.1023/A:1024492725782
[9]	Hintzsche H, Jastrow C, Heinen B, Baaske K, Kleine-Ostmann T, Schwerdtfeger M, Shakfa M K, Kärst U, Koch M, Schrader T and Stopper H 2013 Radiat. Res. 179 38 doi: 10.1667/RR3077.1
[10]	Amicis A D, Sanctis S D, Cristofaro S D, Franchini V, Lista F, Regalbuto E, Giovenale E, Gallerano G P, Nenzi P, Bei R, Fantini M, Benvenuto M, Masuelli L, Coluzzi E, Cicia C and Sgura A 2015 Mutat. Res. Genet. Toxicol. Environ. Mutagen. 793 150 doi: 10.1016/j.mrgentox.2015.06.003
[11]	Borovkova M, Serebriakova M, Fedorov V, Sedykh E, Vaks V, Lichutin A, Salnikova A and Khodzitsky M 2017 Biomed. Opt. Express 8 273 doi: 10.1364/BOE.8.000273
[12]	Wilmink G J, Rivest B D, Roth C C, Ibey B L, Payne J A, Cundin L X, Grundt J E, Peralta X, Mixon D G and Roach W P 2011 Lasers Surg. Med. 43 152 doi: 10.1002/lsm.20960
[13]	Bock J, Fukuyo Y, Kang S, Phipps M L, Alexandrov L B, Rasmussen K O Bishop A R, Rosen E D, Martinez J S, Chen H, Rodriguez G, Alexandrov B S and Usheva A 2010 Plos One 5 e15806
[14]	Alexandrov B S, Rasmussen K O Bishop A R, Usheva A, Alexandrov L B, Chong S, Dagon Y, Booshehri L G, Mielke C H, Phipps M L, Martinez J S, Chen H and Rodriguez G 2011 Biomed. Opt. Express 2 2679 doi: 10.1364/BOE.2.002679
[15]	Alexandrov B S, Phipps M L, Alexandrov L B, Booshehri L G, Erat A, Zabolotny J, Mielke C H, Chen H, Rodriguez G, Rasmussen K O Martinez J S, Bishop A R and Usheva A 2013 Sci. Rep. 3 1184 doi: 10.1038/srep01184
[16]	Titova L V, Ayesheshim A K, Golubov A, Rodriguez-Juarez R, Woycicki R, Hegmann F A and Kovalchuk O 2013 Sci. Rep. 3 2363 doi: 10.1038/srep02363
[17]	Titova L V, Ayesheshim A K, Golubov A, Fogen D, Rodriguez-Juarez R, Hegmann F A and Kovalchuk O 2013 Biomed. Opt. Express 4 559 doi: 10.1364/BOE.4.000559
[18]	Bogomazova A N, Vassina E M, Goryachkovskaya T N, Popik V M, Sokolov A S, Kolchanov N A, Lagarkova M A, Kiselev S L and Peltek S E 2015 Sci. Rep. 5 7749 doi: 10.1038/srep07749
[19]	Iomdina E N, Goltsman G N, Seliverstov S V, Sianosyan A A, Teplyakova K O and Rusova A A 2016 J. Biomed. Opt. 21 97002 doi: 10.1117/1.JBO.21.9.097002
[20]	Liu W, Lu Y, Jiao G, Chen X, Zhou Z, She R, Li J, Chen S, Dong Y and Lü J 2016 Chin. Phys. B 25 060702 doi: 10.1088/1674-1056/25/6/060702
[21]	Hebling J, Almasi G, Kozma I and Kuhl J 2002 Opt. Express 10 1161 doi: 10.1364/OE.10.001161
[22]	Kunitski M, Richter M, Thomson M D, Vredenborg A, Wu J, Jahnke T, Schöffler M, Schmidt-Böcking H, Roskos H G and Dörner R 2013 Opt. Express 21 6826 doi: 10.1364/OE.21.006826
[23]	Kristensen T T, Withayachumnankul W, Jepsen P U and Abbott D 2010 Opt. Express 18 4727 doi: 10.1364/OE.18.004727
[24]	Zheng X, Cui H, Yin Y, Zhang Y, Zong R, Bao X, Ma J, Liu Z and Zhou Y 2017 Invest. Ophth. Vis. Sci. 58 2874 doi: 10.1167/iovs.17-21544
[25]	Wang Z, Gerstein M and Snyder M 2009 Nat. Rev. Genet. 10 57 doi: 10.1038/nrg2484
[26]	Mortazavi A, Williams B A, McCue K, Schaeffer L and Wold B 2008 Nat. Methods 5 621 doi: 10.1038/nmeth.1226
[27]	Robinson M D, McCarthy D J and Smyth G K 2010 Bioinformatics 26 139 doi: 10.1093/bioinformatics/btp616
[28]	Benjamini Y and Yekutieli Y 2001 Ann. Stat. 29 1165 doi: 10.1214/aos/1013699998
[29]	Robinson D R, Wu Y M and Lin S F 2000 Oncogene 19 5548 doi: 10.1038/sj.onc.1203957
[30]	Zwick E, Bange J and Ullrich A 2001 Endocr. Relat. Cancer 8 161
[31]	Belov A A and Mohammadi M 2005 Nat. Rev. Mol. Cell Bio. 6 386 doi: 10.1038/nrm1645
[32]	Franchini V, Sanctis S D, Marinaccio J, Amicis A D, Coluzzi E, Cristofaro S D, Lista F, Regalbuto E, Doria A, Giovenale E, Gallerano G P, Bei R, Benvenuto M, Masuelli L, Udroiu I and Sgura A 2018 Environ. Mol. Mutagen. 57 476
[33]	Matlin A J, Clark F and Smith C W J 2005 Nat. Rev. Mol. Cell Bio. 6 386 doi: 10.1038/nrm1645
[34]	Lister R, Pelizzola M, Dowen R H, Hawkins R D, Hon G, Tonti-Filippini J, Nery J R, Lee L, Ye Z, Ngo Q, Edsall L, Antosiewicz-Bourget J, Stewart R, Ruotti V, Millar A H, Thomson J A, Ren B and Ecker J R 2009 Nature 462 315 doi: 10.1038/nature08514
[35]	Kulipanov G N, Gavrilov N G, Knyazev B A, Kolobanov E I, Kotenkov V V, Kubarev V V, Matveenko A N, Medvedev L E, Miginsky S V, Mironenko L A, Ovchar V K, Popik V M, Salikova T V, Scheglov M A, Serednyakov S S, Shevchenko O A, Skrinsky A N, Tcheskidov V G and Vinokurov N A 2009 Bioelectromagnetics 30 167 doi: 10.1002/bem.20466
[36]	Homenko A, Kapilevich B, Kornstein R and Firer M A 2009 Bioelectromagnetics 30 167 doi: 10.1002/bem.20466
[37]	Fröhlich H 1968 Int. J. Quantum Chem. 2 641 doi: 10.1002/qua.560020505
[38]	Alexandrov B S, Gelev V, Yoo S W, Alexandrov L B, Fukuyo Y, Bishop A R, Ø K and Usheva A 2010 Nucleic Acids Res. 38 1790 doi: 10.1093/nar/gkp1084

Effect of terahertz pulse on gene expression in human eye cells

Effect of terahertz pulse on gene expression in human eye cells

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