中国物理B ›› 2019, Vol. 28 ›› Issue (4): 44302-044302.doi: 10.1088/1674-1056/28/4/044302
• ELECTROMAGNETISM, OPTICS, ACOUSTICS, HEAT TRANSFER, CLASSICAL MECHANICS, AND FLUID DYNAMICS • 上一篇 下一篇
Influence exerted by bone-containing target body on thermoacoustic imaging with current injection
Yan-Hong Li(李艳红), Guo-Qiang Liu(刘国强), Jia-Xiang Song(宋佳祥), Hui Xia(夏慧)
- 1 Institute of Electrical Engineering, Chinese Academy of Sciences, Beijing 100190, China;
2 University of Chinese Academy of Sciences, Beijing 100049, China
Influence exerted by bone-containing target body on thermoacoustic imaging with current injection
Yan-Hong Li(李艳红)1,2, Guo-Qiang Liu(刘国强)1,2, Jia-Xiang Song(宋佳祥)1,2, Hui Xia(夏慧)1
- 1 Institute of Electrical Engineering, Chinese Academy of Sciences, Beijing 100190, China;
2 University of Chinese Academy of Sciences, Beijing 100049, China
摘要：
Thermoacoustic imaging with current injection (TAI-CI) is a novel imaging technology that couples with electromagnetic and acoustic research, which combines the advantages of high contrast of the electrical impedance tomography and the high spatial resolution of sonography, and therefore has the potential for early diagnosis. To verify the feasibility of TAI-CI for complex bone-containing biological tissues, the principle of TAI-CI and the coupling characteristics of fluid and solid were analyzed. Meanwhile, thermoacoustic (TA) effects for fluid model and fluid-solid coupling model were analyzed by numerical simulations. Moreover, we conducted experiments on animal cartilage, hard bone and biological soft tissue phantom with low conductivity (0.5 S/m). By injecting a current into the phantom, the thermoacoustic signal was detected by the ultrasonic transducer with a center frequency of 1 MHz, thereby the B-scan image of the objects was obtained. The B-scan image of the cartilage experiment accurately reflects the distribution of cartilage and gel, and the hard bone has a certain attenuation effect on the acoustic signal. However, compared with the ultrasonic imaging, the thermoacoustic signal is only attenuated during the outward propagation. Even in this case, a clear image can still be obtained and the images can reflect the change of the conductivity of the gel. This study confirmed the feasibility of TAI-CI for the imaging of biological tissue under the presence of cartilage and the bone. The novel TAI-CI method provides further evidence that it can be used in the diagnosis of human diseases.
中图分类号: (Thermoacoustics, high temperature acoustics, photoacoustic effect)
- 43.35.Ud