中国物理B ›› 2009, Vol. 18 ›› Issue (12): 5566-5574.doi: 10.1088/1674-1056/18/12/072

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Inverse computation for cardiac sources using single current dipole and current multipole models

陆宏1, 唐雪正1, 华宁1, 唐发宽1, 王倩2, 马平2   

  1. (1)Department of Cardiology, the 309th Hospital of PLA, Beijing 100091, China; (2)Department of Physics, State Key Laboratory for Artificial Microstructure and Mesoscopic Physics, Peking University, Beijing 100871, China
  • 收稿日期:2009-07-13 修回日期:2009-08-07 出版日期:2009-12-20 发布日期:2009-12-20
  • 基金资助:
    Project supported by the State Key Development Program for Basic Research of China (Grant No 2006CB601007), the National Natural Science Foundation of China (Grant No 10674006) and the National High Technology Research and Development Program of China (Gr

Inverse computation for cardiac sources using single current dipole and current multipole models

Wang Qian(王倩)a),Ma Ping(马平) a)†,Lu Hong(陆宏)b), Tang Xue-Zheng(唐雪正)b),Hua Ning(华宁) b), and Tang Fa-Kuan(唐发宽)b)‡   

  1. a Department of Physics, State Key Laboratory for Artificial Microstructure and Mesoscopic Physics, Peking University, Beijing 100871, China; b Department of Cardiology, the 309th Hospital of PLA, Beijing 100091, China
  • Received:2009-07-13 Revised:2009-08-07 Online:2009-12-20 Published:2009-12-20
  • Supported by:
    Project supported by the State Key Development Program for Basic Research of China (Grant No 2006CB601007), the National Natural Science Foundation of China (Grant No 10674006) and the National High Technology Research and Development Program of China (Gr

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摘要： Two cardiac functional models are constructed in this paper. One is a single current model and the other is a current multipole model. Parameters denoting the properties of these two models are calculated by a least-square fit to the measurements using a simulated annealing algorithm. The measured signals are detected at 36 observation nodes by a superconducting quantum interference device (SQUID). By studying the trends of position, orientation and magnitude of the single current dipole model and the current multipole model in the QRS complex during one time span and comparing the reconstructed magnetocardiography (MCG) of these two cardiac models, we find that the current multipole model is a more appropriate model to represent cardiac electrophysiological activity.

Abstract: Two cardiac functional models are constructed in this paper. One is a single current model and the other is a current multipole model. Parameters denoting the properties of these two models are calculated by a least-square fit to the measurements using a simulated annealing algorithm. The measured signals are detected at 36 observation nodes by a superconducting quantum interference device (SQUID). By studying the trends of position, orientation and magnitude of the single current dipole model and the current multipole model in the QRS complex during one time span and comparing the reconstructed magnetocardiography (MCG) of these two cardiac models, we find that the current multipole model is a more appropriate model to represent cardiac electrophysiological activity.

Key words: magnetocardiography, inverse computation, cardiac source model

中图分类号:  (Biological signal processing)

  • 87.85.Ng
02.60.Pn (Numerical optimization) 85.25.Dq (Superconducting quantum interference devices (SQUIDs)) 87.19.Hh (Cardiac dynamics) 87.19.R- (Mechanical and electrical properties of tissues and organs)