中国物理B ›› 2008, Vol. 17 ›› Issue (11): 4100-4106.doi: 10.1088/1674-1056/17/11/024
唐 军1, 易 鸣2, 马 军3, 贾 亚4
Tang Jun (唐 军)ab, Ma Jun (马 军)bc, Yi Ming (易 鸣)b, Jia Ya (贾 亚)c
摘要: The effect of change in concentration of messenger molecule inositol 1,4,5-trisphosphate (IP$_{3})$ on intracellular Ca$^{2 + }$spiral pattern evolution is studied numerically. The results indicate that when the IP$_{3}$ concentration decreases from 0.27 $\mu $M, a physiologically reasonable value, to different values, the spiral centre drifts to the edge of the medium and disappears for a small enough IP$_{3}$ concentration. The instability of spiral pattern can be understood in terms of excitability-change controlled by the IP$_{3}$ concentration. On the other hand, when the IP$_{3}$ concentration increases from 0.27\,$\mu $M, a homogeneous area with a high Ca$^{2 + }$ concentration emerges and competes with the spiral pattern. A high enough IP$_{3}$ concentration can lead the homogeneous area to occupy the whole medium. The instability of spiral pattern is ascribed to the change in stability of a stationary state with a high Ca$^{2 + }$ concentration.
中图分类号: (Active transport processes)