Cardiac magnetic source imaging based on current multipole model

doi:10.1088/1674-1056/20/1/010702

中国物理B ›› 2011, Vol. 20 ›› Issue (1): 10702-010702.doi: 10.1088/1674-1056/20/1/010702

Cardiac magnetic source imaging based on current multipole model

唐发宽¹, 华宁¹, 陆宏¹, 唐雪正¹, 王倩², 马平³

(1)Department of Cardiology, The 309th Hospital of PLA, Beijing 100091, China; (2)Department of Cardiology, The 309th Hospital of PLA, Beijing 100091, China;Department of Physics, State Key Laboratory for Artificial Microstructure and Mesoscopic Physics, Peking University, Beijing 100871, China; (3)Department of Physics, State Key Laboratory for Artificial Microstructure and Mesoscopic Physics, Peking University, Beijing 100871, China

收稿日期:2010-05-23 修回日期:2010-08-04 出版日期:2011-01-15 发布日期:2011-01-15
基金资助:
Project supported by the State Key Development Program for Basic Research of China (Grant No. 2006CB601007), the National Natural Science Foundation of China (Grant No. 10674006), and the National High Technology Research and Development Program of China (Grant No. 2007AA03Z238).

Cardiac magnetic source imaging based on current multipole model

Tang Fa-Kuan(唐发宽)^a),Wang Qian(王倩)^a)b), Hua Ning(华宁)^a), Lu Hong(陆宏)^a), Tang Xue-Zheng(唐雪正)^a),and Ma Ping(马平)^b)^†

^a Department of Cardiology, The 309th Hospital of PLA, Beijing 100091, China; ^b Department of Physics, State Key Laboratory for Artificial Microstructure and Mesoscopic Physics, Peking University, Beijing 100871, China

Received:2010-05-23 Revised:2010-08-04 Online:2011-01-15 Published:2011-01-15
Supported by:
Project supported by the State Key Development Program for Basic Research of China (Grant No. 2006CB601007), the National Natural Science Foundation of China (Grant No. 10674006), and the National High Technology Research and Development Program of China (Grant No. 2007AA03Z238).

摘要/Abstract

摘要： It is widely accepted that the heart current source can be reduced into a current multipole. By adopting three linear inverse methods, the cardiac magnetic imaging is achieved in this article based on the current multipole model expanded to the first order terms. This magnetic imaging is realized in a reconstruction plane in the centre of human heart, where the current dipole array is employed to represent realistic cardiac current distribution. The current multipole as testing source generates magnetic fields in the measuring plane, serving as inputs of cardiac magnetic inverse problem. In the heart-torso model constructed by boundary element method, the current multipole magnetic field distribution is compared with that in the homogeneous infinite space, and also with the single current dipole magnetic field distribution. Then the minimum-norm least-squares (MNLS) method, the optimal weighted pseudoinverse method (OWPIM), and the optimal constrained linear inverse method (OCLIM) are selected as the algorithms for inverse computation based on current multipole model innovatively, and the imaging effects of these three inverse methods are compared. Besides, two reconstructing parameters, residual and mean residual, are also discussed, and their trends under MNLS, OWPIM and OCLIM each as a function of SNR are obtained and compared.

关键词: cardiac magnetic imaging, current multipole, heart-torso model, inverse method

Abstract: It is widely accepted that the heart current source can be reduced into a current multipole. By adopting three linear inverse methods, the cardiac magnetic imaging is achieved in this article based on the current multipole model expanded to the first order terms. This magnetic imaging is realized in a reconstruction plane in the centre of human heart, where the current dipole array is employed to represent realistic cardiac current distribution. The current multipole as testing source generates magnetic fields in the measuring plane, serving as inputs of cardiac magnetic inverse problem. In the heart-torso model constructed by boundary element method, the current multipole magnetic field distribution is compared with that in the homogeneous infinite space, and also with the single current dipole magnetic field distribution. Then the minimum-norm least-squares (MNLS) method, the optimal weighted pseudoinverse method (OWPIM), and the optimal constrained linear inverse method (OCLIM) are selected as the algorithms for inverse computation based on current multipole model innovatively, and the imaging effects of these three inverse methods are compared. Besides, two reconstructing parameters, residual and mean residual, are also discussed, and their trends under MNLS, OWPIM and OCLIM each as a function of SNR are obtained and compared.

Key words: cardiac magnetic imaging, current multipole, heart-torso model, inverse method

中图分类号:

07.05Tp

87.80.-y (Biophysical techniques (research methods)) 87.85.-d (Biomedical engineering)

唐发宽, 王倩, 华宁, 陆宏, 唐雪正, 马平. Cardiac magnetic source imaging based on current multipole model[J]. 中国物理B, 2011, 20(1): 10702-010702.

Tang Fa-Kuan(唐发宽), Wang Qian(王倩), Hua Ning(华宁), Lu Hong(陆宏), Tang Xue-Zheng(唐雪正), and Ma Ping(马平). Cardiac magnetic source imaging based on current multipole model[J]. Chin. Phys. B, 2011, 20(1): 10702-010702.

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Cardiac magnetic source imaging based on current multipole model

Cardiac magnetic source imaging based on current multipole model

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