Potential dynamic analysis of tumor suppressor p53 regulated by Wip1 protein |
Bifurcation diagram of p53 vs p53 degradation rate (dp53): (a) Wip1 synthesis rate vwip1 = 0, (b) vwip1 = 0.046, (c) vwip1 = 0.051 and (d) vwip1 = 0.12. The stable and unstable steady states are indicated by red and black lines, respectively. Green circles and blue circles are the maxima and minima of the stable and unstable limit cycles, respectively. |