High-contrast imaging based on wavefront shaping to improve low signal-to-noise ratio photoacoustic signals using superpixel method<xref rid="cpb_29_3_034301fn1" ref-type="fn">*</xref><fn id="cpb_29_3_034301fn1"><label>*</label><p>Project supported by the National Key Research and Development Program of China (Grant No. 2017YFB1104500), the Beijing Natural Science Foundation, China (Grant No. 7182091), the National Natural Science Foundation of China (Grant No. 21627813), and the Research Projects on Biomedical Transformation of China-Japan Friendship Hospital (Grant No. PYBZ1801).</p></fn>

High-contrast imaging based on wavefront shaping to improve low signal-to-noise ratio photoacoustic signals using superpixel method**

Project supported by the National Key Research and Development Program of China (Grant No. 2017YFB1104500), the Beijing Natural Science Foundation, China (Grant No. 7182091), the National Natural Science Foundation of China (Grant No. 21627813), and the Research Projects on Biomedical Transformation of China-Japan Friendship Hospital (Grant No. PYBZ1801).

Lv Xinjing¹, Xu Xinyu¹, Feng Qi¹, Zhang Bin², Ding Yingchun^{1, †}, Liu Qiang^{2, ‡}

(a) Scanning image with the unprocessed signals. (b) The image amplitude distribution along the white line in (a). (c) Scanning image with the denoised signals. (d) The image amplitude distribution along the white line in (c). The insets represent the optimal superpixel mask.