High-contrast imaging based on wavefront shaping to improve low signal-to-noise ratio photoacoustic signals using superpixel method<xref rid="cpb_29_3_034301fn1" ref-type="fn">*</xref><fn id="cpb_29_3_034301fn1"><label>*</label><p>Project supported by the National Key Research and Development Program of China (Grant No. 2017YFB1104500), the Beijing Natural Science Foundation, China (Grant No. 7182091), the National Natural Science Foundation of China (Grant No. 21627813), and the Research Projects on Biomedical Transformation of China-Japan Friendship Hospital (Grant No. PYBZ1801).</p></fn>

High-contrast imaging based on wavefront shaping to improve low signal-to-noise ratio photoacoustic signals using superpixel method**

Project supported by the National Key Research and Development Program of China (Grant No. 2017YFB1104500), the Beijing Natural Science Foundation, China (Grant No. 7182091), the National Natural Science Foundation of China (Grant No. 21627813), and the Research Projects on Biomedical Transformation of China-Japan Friendship Hospital (Grant No. PYBZ1801).

Lv Xinjing¹, Xu Xinyu¹, Feng Qi¹, Zhang Bin², Ding Yingchun^{1, †}, Liu Qiang^{2, ‡}

(a) The random signal before and after denoising. The blue curve represents the raw signal without denoising. The red curve represents the signal after denoising. (b) Scanning image reconstructed with the raw signals. (c) Scanning image reconstructed with the denoised signals. The insets represented the random superpixel mask.