Phase transition of DNA compaction in confined space: Effects of macromolecular crowding are dominant*

Project supported by the National Natural Science Foundation of China (Grant Nos. 11464004 and 11864006), the State Scholarship Fund, China (Grant No. 20173015) and Guizhou Scientific and Technological Program, China (Grant No. 20185781).

Chen Erkun1, Fan Yangtao2, Zhao Guangju1, Mao Zongliang1, Zhou Haiping3, ‡, Liu Yanhui1, §
       

Representation of condensed DNA in the confined spherical space without crowders (a) and that in the presence of crowders (b). R, d m, d c, r cc and r mc are the radius of confined spherical space, the diameter of DNA, the diameter of crowder, the distance between the center of crowders, the distance between the center of crowder and central line of DNA, respectively.