Quantitative heterogeneity and subgroup classification based on motility of breast cancer cells

Xiong Ling¹, Liu Yanping^{1, 2}, Liu Ruchuan¹, Yuan Wei³, Wang Gao¹, He Yi¹, Shuai Jianwei², Jiao Yang⁴, Zhang Xixiang⁵, Han Weijing⁶, Qu Junle^{3, ‡}, Liu Liyu^{1, §}

Motility of the two breast cancer cell lines. (a) Trajectories of MDA-MB-231 breast tumor cells show a larger range of motion after EGF addition. (b)The average MSD vs. time for MDA-MB-231 cells and MCF-7 cells in EGF- and EGF+ medium conditions. (c)The speed histograms of MDA-MB-231 and MCF-7 cells in two medium conditions.