The determinant factors for map resolutions obtained using CryoEM single particle imaging method Project supported by the National Natural Science Foundation of China (Grant Nos. 11774011, 11434001, U1530401, and U1430237). |
(color online) The workflow for single particle imaging data stimulation. (a) The protocol for the projection data simulation with defocused lenses and Gaussian noises from a single 3D structure. (b) The procedure for structure ensemble generation to model the heterogeneity of biomolecular conformations. |