Efficiency of collective myosin II motors studied with an elastic coupling power-stroke ratchet model*

Project supported by the Key Research Program of Frontier Sciences of Chinese Academy of Sciences (Grant No. Y7Y1472Y61), the National Natural Science Foundation of China (Grant Nos. 11205123, 11574329, 11774358, 11747601, and 11675017), the Joint NSFC-ISF Research Program (Grant No. 51561145002), the CAS Biophysics Interdisciplinary Innovation Team Project (Grant No. 2060299), the CAS Strategic Priority Research Program (Grant No. XDA17010504), and the Fundamental Research Funds for the Central Universities (Grant No. 2017EYT24).

Wang Zi-Qing1, Li Jin-Fang1, Xie Ying-Ge1, Wang Guo-Dong1, Shu Yao-Gen2, †
       

(color online) Schematic model of Model I under consideration of power stroke (Model II). (a) The process from A to B represents the power-stroke, while the process from B to C does the recovery process of power-stroke. in recovery process motor head detaches from the thin filament due to ATP excitation and the lever arm reprimes.(b) In modified W1, there is a reflection boundary that forbids motor to transit directly from one W1 well to another one. At the same time, both transitions between W1 and W2, i.e., ωon and ωoff, are localized at right side (A) and left side (B) of the reflection boundary by Θ(z) and Φ(z) respectively. The joint point in coordinate z (marked by red star in panel (a)) of motor stalk (spring) and lever arm equivalents to the position of motor head domain in Model I.