Treatable focal region modulated by double excitation signal superimposition to realize platform temperature distribution during transcranial brain tumor therapy with high-intensity focused ultrasound*

Project supported by the National Natural Science Foundation of China (Grant No. 81272495) and the Natural Science Foundation of Tianjin, China (Grant No. 16JC2DJC32200).

Chang Shi-Hui1, Cao Rui2, Zhang Ya-Bin1, 3, Wang Pei-Guo4, Wu Shi-Jing1, Qian Yu-Han1, Jian Xi-Qi1, †
       

(color online) Temperature distributions with different values of Δt in an acoustic wave period with targets both set on acoustic axis and maximum focal temperature of 65 °C (L = 10.0 mm, M = 0.50, and Pw = 103.05 W).