Treatable focal region modulated by double excitation signal superimposition to realize platform temperature distribution during transcranial brain tumor therapy with high-intensity focused ultrasound*

Project supported by the National Natural Science Foundation of China (Grant No. 81272495) and the Natural Science Foundation of Tianjin, China (Grant No. 16JC2DJC32200).

Chang Shi-Hui1, Cao Rui2, Zhang Ya-Bin1, 3, Wang Pei-Guo4, Wu Shi-Jing1, Qian Yu-Han1, Jian Xi-Qi1, †
       

(color online) Temperature field with F1 set to be at (0, 1, 75) and F2 set to be at different locations with uniform temperature distribution in the y direction and maximum focal temperature of 65 °C (Pw = 103.05 W). (a) F2 (0, −1, 77.5), (b) F2 (0, −1, 80).