Solvent effects and potential of mean force study of the SN2 reaction of CH3+CN− in water
Li Chen, Liu Peng, Li Yongfang, Wang Dunyou ‡
       

(color online) Comparison between the potential energy profiles calculated along the NEB reaction pathway in gas phase (red) and in aqueous solution (blue) for the title reaction CH 3 F + CN − → CH 3 CN + F − . The black numbers denote the experimental values and the green numbers denote the calculated values using gas-phase data.