Lipoprotein in cholesterol transport: Highlights and recent insights into its structural basis and functional mechanism

Chen Shu-Yu, Li Na, Jin Tao-Li, Gou Lu, Hao Dong-Xiao, Tian Zhi-Qi, Zhang Sheng-Li, Zhang Lei^‡

(color online) The crystal structure of CETP (PDB: 2OBD) and three-dimensional density maps of CETP binging lipoproteins, (a) atom figure of CETP, (b) secondary structure of CETP, (c) ternary complexes of HDL-CETP-LDL in cryo-EM micrographs, (d)–(f) the CETP insert into HDL, VLDL, LDL respectively in cryo-EM micrographs, (g) the tunnel model of CETP-mediated lipid transfer, (Ref. [105]).