The birhythmicity increases the diversity of p53 oscillation induced by DNA damage

Wang Dao-Guang^{1, 2}, Zhou Chun-Hong², Zhang Xiao-Peng^{1, 3, †}

Noise-induced variability in p53 oscillations. The first column shows the temporal evolution of [p53_p] at (from top to bottom). The second and third columns show the histograms of the amplitude and period, respectively. In each case, 500 runs of simulations lasting 3000 min are performed.