Computational study of non-catalytic T-loop pocket on CDK proteins for drug development<xref rid="cpb_26_12_128702_fn1" ref-type="fn">*</xref> <fn id="cpb_26_12_128702_fn1"> <label>*</label> <p>Project supported by the National Natural Science Foundation of China (Grant No. 11704140), the Natural Science Foundation of Hubei Province, China (Grant No. 2017CFB116), the Thousand Talents Plan (Grant No. 31103201603), and the Self-determined Research Funds of CCNU from the Colleges’ Basic Research and Operation of MOE 20205170045 to YZ.</p> </fn>

Computational study of non-catalytic T-loop pocket on CDK proteins for drug development* *

Project supported by the National Natural Science Foundation of China (Grant No. 11704140), the Natural Science Foundation of Hubei Province, China (Grant No. 2017CFB116), the Thousand Talents Plan (Grant No. 31103201603), and the Self-determined Research Funds of CCNU from the Colleges’ Basic Research and Operation of MOE 20205170045 to YZ.

Wang Huiwen¹, Wang Kaili¹, Guan Zeyu¹, Jian Yiren^{2, 4}, Jia Ya¹, Kashanchi Fatah³, Zeng Chen^{1, 2, †}, Zhao Yunjie^{1, ‡}

(color online) The top five detected pockets (shown as surface representation) together with a cartoon representation of CDK2 protein (PDB code: 1FIN). The main shape descriptors (volume and surface) for the top 5 detected pockets are shown in the table on right.