Anisotropic formation mechanism and nanomechanics for the self-assembly process of cross-β peptides*

Project supported by the National Basic Research Program of China (Grant No. 2013CB932804), the National Natural Science Foundation of China (Grant Nos. 11421063, 11647601, 11504431, and 21503275), the Scientific Research Foundation of China University of Petroleum (East China) for Young Scholar (Grant Y1304073). YantingWang also thanks the financial support through the CAS Biophysics Interdisciplinary Innovation Team Project (Grant No. 2060299).

Deng Li1, Zhao Yurong1, Zhou Peng1, Xu Hai1, Wang Yanting2, 3, †
       

(color online) Short-range non-bonded energies between the hydrophobic side chains and solvents around the sheets in different shells as a function of ξ for the inter-sheet structure at T = 300 K. Panels (a), (b), (c), and (d) correspond to the shells from 0.2 nm to 0.3 nm, 0.3 nm to 0.4 nm, 0.4 nm to 0.5 nm, and 0.5 nm to 0.6 nm, respectively.