Silicon quantum dots delivered phthalocyanine for fluorescence guided photodynamic therapy of tumor |
(color online) Intracellular localization and photostability of (Si+Pc) NPs. (a) Representative MGC-803 cells which are treated with (Si+Pc) NPs for 24 h and labelled with LysoTracker (green fluorescence) for 30 min prior to confocal imaging. (b) Fluorescence stabilities of the Si, Pc, and LysoTracker in cells, under continuous laser exposure for 20 min and 40 min in situ. The cells are treated with (Si+Pc) NPs (at 1.2 mg⋅mL−1 for 24 h) and LysoTracker (for 30 min). (c) Time-dependent normalized fluorescence intensity in each channel integrated from panel (b). Error bars are based on the SD of more than 30 cells in three parallel samples. |