(color online) Native stability of 1YRF tested by hyCG and AA. (a) Backbone RMSD, in which the red represents hyCG and green represents AA. The color is also adopted by the other figure. The black line indicates a 3 Å limit for the backbone RMSD threshold. Within this threshold, it is commonly considered as a folded state. (b) and (c) Distribution of two selected distances constructed from the first 50 ns trajectory. (d) Schematic representation of 1YRF native structure and the two selected distances.