Ultrasound-mediated transdermal drug delivery of fluorescent nanoparticles and hyaluronic acid into porcine skin <italic>in vitro</italic>

Ultrasound-mediated transdermal drug delivery of fluorescent nanoparticles and hyaluronic acid into porcine skin in vitro

Wang Huan-Lei^{1, 2}, Fan Peng-Fei¹, Guo Xia-Sheng¹, Tu Juan^{1, †,}, Ma Yong^{3, ‡,}, Zhang Dong¹

Fluorescent nanoparticle penetration (a) depth and (b) concentration in skin samples exposed to 10-min ultrasound with different frequencies and pressure amplitudes, after 5-min pretreatment with UCAs.