Ultrasound-mediated transdermal drug delivery of fluorescent nanoparticles and hyaluronic acid into porcine skin <italic>in vitro</italic>

Ultrasound-mediated transdermal drug delivery of fluorescent nanoparticles and hyaluronic acid into porcine skin in vitro

Wang Huan-Lei^{1, 2}, Fan Peng-Fei¹, Guo Xia-Sheng¹, Tu Juan^{1, †,}, Ma Yong^{3, ‡,}, Zhang Dong¹

20-min after ultrasound treatment, SEM images were obtained for skin samples (a) treated by 10-min ultrasound exposures at 635.5 kHz and 100 kPa, and (b) treated by 60-min ultrasound exposures at 635.5 kHz and 100 kPa.