Uncovering the underlying physical mechanisms of biological systems via quantification of landscape and flux
Xu Li1, †, 
, Chu Xiakun1, Yan Zhiqiang1, Zheng Xiliang1, Zhang Kun1, Zhang Feng1, Yan Han1, Wu Wei1, Wang Jin1, 2, ‡,
, Chu Xiakun1, Yan Zhiqiang1, Zheng Xiliang1, Zhang Kun1, Zhang Feng1, Yan Han1, Wu Wei1, Wang Jin1, 2, ‡, Schematic view illustrating the specificity. (a) Conventional specificity: the same ligand (red) binding to diverse receptors (green) with the corresponding energy spectrum. (b) Intrinsic specificity: a particular ligand binding to diverse binding states (modes) of its receptor. (c) Conventional specificity: the same receptor with diverse ligands.[
