Uncovering the underlying physical mechanisms of biological systems via quantification of landscape and flux
Xu Li1, †, , Chu Xiakun1, Yan Zhiqiang1, Zheng Xiliang1, Zhang Kun1, Zhang Feng1, Yan Han1, Wu Wei1, Wang Jin1, 2, ‡,
       

Energy landscape quantifications during flexible recognition for (a) 2-state and (b) 3-state homodimers. Each homodimer has two individual monomeric folding energy landscapes, one individual interfacial binding energy landscape, and a combined global binding–folding energy landscape. The funnel plot details are the same as Fig. 1.[29]