Uncovering the underlying physical mechanisms of biological systems via quantification of landscape and flux
Xu Li1, †, , Chu Xiakun1, Yan Zhiqiang1, Zheng Xiliang1, Zhang Kun1, Zhang Feng1, Yan Han1, Wu Wei1, Wang Jin1, 2, ‡,
       

(a) The phases with checkpoints for the cell cycle system: the G1 phase, S phase, G2 phase, M phase. (b) G1 phase, S/G2 phase, M phase, G1 checkpoint, and S/G2 checkpoint on the potential landscape. (c) The two-dimensional landscape (the non-zero curl flux is shown in white arrows; the negative gradient of the landscape is shown in red arrows). The diffusion parameter is set asD= 0.05.[11]