Uncovering the underlying physical mechanisms of biological systems via quantification of landscape and flux |
(a) The phases with checkpoints for the cell cycle system: the G1 phase, S phase, G2 phase, M phase. (b) G1 phase, S/G2 phase, M phase, G1 checkpoint, and S/G2 checkpoint on the potential landscape. (c) The two-dimensional landscape (the non-zero curl flux is shown in white arrows; the negative gradient of the landscape is shown in red arrows). The diffusion parameter is set as |