Multifractal analysis of white matter structural changes on 3D magnetic resonance imaging between normal aging and early Alzheimer’s disease

Ni Huang-Jing^a), Zhou Lu-Ping†^b), Zeng Peng^a), Huang Xiao-Lin^a), Liu Hong-Xing^a), Ning Xin-Bao‡^a),

Pearson’s correlation coefficient ρ between the multifractal features and the clinical MMSE scores for (a) Δ α versus MMSE from BCMA; (b) Δ f versus MMSE from BCMA; (c) Δ α versus MMSE from IRBCMA; (d) Δ f versus MMSE from IRBCMA. The circle values (•) are from NC subjects and the diamond values (◊) are from AD subjects. The solid line (—) represents the correlation trend between the two values in the subfigures. p < 0.001 indicates the statistical significance for the Pearson’s correlation coefficient.